Should colonoscopy be performed in patients with cryptogenic liver abscess?

Clinics and Research in Hepatology and Gastroenterology
Hyun Cheol KooBoo Sung Kim

Abstract

The interruption of a mucosal barrier by colon cancer or a polyp can lead to the development of a liver abscess. This study aimed to evaluate the possible contribution of colon cancer to the development of liver abscess and the necessity of colonoscopy in patients presenting with cryptogenic liver abscess. We reviewed the medical records of 268 patients diagnosed with liver abscess between January 2001 and April 2010. Among cases with no definite cause of liver abscess, differences between patients with and without colon cancer were evaluated in terms of clinical, laboratory, imaging, and microbiological findings. Pyogenic liver abscess with no apparent etiology was encountered 163 patients; colonoscopy was performed in 121 of these 163 patients. The tumor diagnosis was confirmed by total colonoscopy in 12/163 (7.4%) patients with adenocarcinoma and 8/163 (4.9%) patients with high-grade dysplasia. Nine patients were diagnosed with stage I, two patients with stage II, and one with stage III disease according to the tumor, nodes, and metastases (TNM) staging system for colorectal cancer. The prevalence of incidental colon cancer in patients with pyogenic liver abscess was significantly higher than that of normal individuals who u...Continue Reading

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Citations

Oct 17, 2018·QJM : Monthly Journal of the Association of Physicians·V H ChongC P Lin
Jan 19, 2019·QJM : Monthly Journal of the Association of Physicians·V H Chong, C F Chong
May 20, 2017·World Journal of Gastroenterology : WJG·Ming-Jen TsaiSolomon Chih-Cheng Chen
Oct 27, 2016·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Nae Yun HeoMinkyung Oh
Dec 9, 2014·Clinical Liver Disease·Shiva K Ratuapli, Hugo E Vargas

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