Should obesity be blamed for the high prevalence rates of hypertension in black South African women?

Journal of Human Hypertension
Aletta Elisabeth SchutteN T Malan

Abstract

Hypertension is highly prevalent in South Africa, resulting in high stroke mortality rates. Since obesity is very common among South African women, it is likely that obesity contributes to the hypertension prevalence. The aims were to determine whether black African women have higher blood pressures (BPs) than Caucasian women, and whether obesity is related to their cardiovascular risk. African (N=102) and Caucasian (N=115) women, matched for age and body mass index, were included. Correlations between obesity (total body fat, abdominal obesity and peripheral fat) and cardiovascular risk markers (haemodynamic parameters, lipids, inflammatory markers, prothrombotic factors, adipokines, HOMA-IR (homoeostasis model assessment insulin resistance)) were compared between the ethnic groups (adjusted for age, smoking, alcohol and physical activity). Comparisons between low- and high-BP groups were also made for each ethnic group. Results showed that African women had higher BP (P<0.01) with increased peripheral vascular resistance. Surprisingly, African women showed significantly weaker correlations between obesity measures and cardiovascular risk markers when compared to Caucasian women (specifically systolic BP, arterial resistance, ...Continue Reading

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Citations

Aug 31, 2011·Metabolic Syndrome and Related Disorders·W John KalkAnne E Sumner
Oct 15, 2008·European Heart Journal·Gregory Y H Lip, Mehmood Butt
Mar 27, 2012·Cardiovascular Journal of Africa·Claire M TolmayJohannes M van Rooyen
Oct 31, 2012·Cardiovascular Journal of Africa·Bridget AdeboyeCatherine Rolland
Dec 14, 2011·Clinical and Experimental Hypertension : CHE·Hugo Willem HuismanLeone Malan
Jul 10, 2010·Regulatory Peptides·Aletta Elisabeth SchutteNicolaas Theodore Malan
Dec 20, 2011·Psychophysiology·Manja ReimannLeoné Malan
Jul 21, 2014·Metabolism: Clinical and Experimental·Susann Blüher, Peter Schwarz
Mar 24, 2017·Journal of Human Hypertension·A E SchutteH W Huisman

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