PMID: 7086982May 1, 1982Paper

Should patients with single renal stone occurrence undergo diagnostic evaluation?

The Journal of Urology
C Y Pak


Diagnostic evaluation was conducted on 34 patients with a single episode of renal stone formation. Absorptive hypercalciuria as disclosed in 55.9 per cent (23.5 percent type I and 32.4 per cent type II), renal hypercalciuria in 11.8 per cent, primary hyperparathyroidism in 2.9 per cent, hyperuricosuric calcium oxalate nephrolithiasis in 8.8 per cent and no metabolic abnormality in 20.6 per cent. Compared to the group with recurrent stone formation the group with a single stone episode had just as severe biochemical abnormalities or laboratory results, such as hypercalciuria and exaggerated calciuric response to oral calcium load in absorptive hypercalciuria, high fasting urinary calcium and cyclic adenosine monophosphate in renal hypercalciuria, hyperuricosuria in hyperuricosuria calcium oxalate nephrolithiasis and low urine volume in no metabolic abnormality. The results suggest that the same physiological and environmental disturbances characterize stone formation in patients with a single stone episode as in those with recurrent stone formation and indicate the need for diagnostic evaluation.


Mar 6, 1975·The New England Journal of Medicine·C Y PakO Waters
Jan 1, 1979·Nephron·C Y Pak
May 1, 1978·Kidney International·E R Yendt, M Cohanim
Jun 1, 1976·Metabolism: Clinical and Experimental·C Y Pak, K Holt
Aug 1, 1974·The Journal of Clinical Investigation·C Y PakW Snyder
Dec 19, 1974·The New England Journal of Medicine·F L Coe, A G Kavalach
Jan 1, 1973·The Journal of Clinical Investigation·F L CoeE Reiss
Jan 24, 1974·The New England Journal of Medicine·C Y PakF C Bartter
Oct 1, 1981·The American Journal of Medicine·C Y PakN A Breslau
Jan 1, 1980·The Journal of Urology·U BackmanB Wikström
Jul 1, 1980·Annals of Internal Medicine·C Y PakL Brinkley


Apr 1, 1989·The Journal of Urology·L A Miller, F B Stapleton
Dec 1, 1983·The Journal of Urology·D H HoskingL H Smith
Sep 1, 1999·BJU International·R KocvaraJ Dvorácek
Jul 11, 2003·The Journal of Urology·Ying-Huei LeeJong-Khing Huang
Aug 7, 2014·Urolithiasis·Pietro Manuel FerraroGambaro Giovanni
Jan 1, 1987·International Urology and Nephrology·S HadidyA Kharma
Jan 1, 1984·Urologic Radiology·K N Van Arsdalen
Dec 23, 1999·Journal of Endourology·D A LifshitzA P Evan
Apr 28, 2001·Journal of Endourology·J KourambasG M Preminger
Feb 24, 2007·Nephrology·Peter Hughes, Caring for Australians with Renal Impairment (CARI)
Nov 5, 2014·Urolithiasis·Andreas SkolarikosThomas Knoll
Jun 8, 2018·International Urology and Nephrology·Yasmin Abu-GhanemDorit E Zilberman
Oct 18, 2016·The Journal of Urology·Ryan S HsiMarshall L Stoller
Jan 1, 1986·The Journal of Urology·B GoldwasserC C Carson
Jul 20, 2010·The Journal of Urology·Scott M CastleMarshall L Stoller
Mar 1, 1995·Annals of Clinical Biochemistry·C T Samuell, G P Kasidas

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