Should we use closed or open infusion containers for prevention of bloodstream infections?

Annals of Clinical Microbiology and Antimicrobials
Manuel Sigfrido Rangel-FraustoVictor Daniel Rosenthal

Abstract

Hospitalized patients in critical care settings are at risk for bloodstream infections (BSI). Most BSIs originate from a central line (CL), and they increase length of stay, cost, and mortality. Open infusion containers may increase the risk of contamination and administration-related (CLAB) because they allow the entry of air into the system, thereby also providing an opportunity for microbial entry. Closed infusion containers were designed to overcome this flaw. However, open infusion containers are still widely used throughout the world.The objective of the study was to determine the effect of switching from open (glass, burettes, and semi-rigid) infusion containers to closed, fully collapsible, plastic infusion containers (Viaflex) on the rate and time to onset of central line-associated bloodstream infections CLABs. An open label, prospective cohort, active healthcare-associated infection surveillance, sequential study was conducted in four ICUs in Mexico. Centers for Disease Control National Nosocomial Infections Surveillance Systems definitions were used to define device-associated infections. A total of 1,096 adult patients who had a central line in place for >24 hours were enrolled. The CLAB rate was significantly high...Continue Reading

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Citations

Jul 19, 2011·Applied Health Economics and Health Policy·Robin S TurpinPaul Wischmeyer
Dec 3, 2010·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Dennis G MakiManuel Sigfrido Rangel-Frausto
May 1, 2017·European Journal of Hospital Pharmacy. Science and Practice·Eeva Suvikas-PeltonenMarja Airaksinen

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