PMID: 8883835Sep 1, 1996

Shrinkage and recovery of cells of the lateral geniculate nuclei with prism-rearing in macaques

Behavioural Brain Research
M L Crawford, G K von Noorden

Abstract

Infant macaque monkeys (Macaca mulatta) were subjected to optical dissociation of binocular vision by wearing prisms before their eyes for 30 days, beginning about 30 days of age. Such treatment mimicked strabismus during infancy and resulted in a dramatic loss of cortical binocular neurons. A concurrent shrinkage of 21% was found in the cells of the lateral geniculate nuclei (LGN) at the end of a terminal electrophysiological study at 60 days of age. A group of monkeys surviving for 5 years showed recovery of normal cell size, even though they did not recover functional binocular neurons in visual cortex.

References

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Sep 1, 1996·Behavioural Brain Research·M L CrawfordG K von Noorden

Citations

Oct 1, 1983·Behavioural Brain Research·L J Garey, C de Courten
Sep 1, 1996·Behavioural Brain Research·M L CrawfordG K von Noorden
Sep 1, 1996·Behavioural Brain Research·M L CrawfordG K von Noorden
Dec 10, 2013·Cell Reports·Kohei YoshitakeKatsuei Shibuki
Dec 20, 2007·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Helen LewSeung-Han Han
Nov 5, 2008·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Roger W WestJulia K Sawyer
Dec 15, 2010·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Roger W West
Mar 26, 2009·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Mitchell ScheimanG Lynn Mitchell
Aug 4, 2009·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Glyn Walsh
Jul 27, 2005·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Mitchell ScheimanJanice Wensveen
Dec 26, 2009·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Roger W West

Related Concepts

Metazoa
Electrophysiology (Science)
Medial Geniculate Body
Macaca mulatta
Neurons
Visual Cortex
Vision, Binocular
Cell Volume

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