SIADH: a case review

Neonatal Network : NN
L Shirland

Abstract

Because the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) can cause neurologic sequelae with the potential to affect long-term outcomes, its prompt recognition and treatment are essential. Normally, antidiuretic hormone (ADH) is secreted when effective circulating blood volume is decreased. SIADH is marked by secretion of ADH in the presence of effective or normal circulating blood volume. This causes plasma hyponatremia simultaneously with plasma hypo-osmolality and inappropriate hyperosmolality of the urine. This article explains the pathophysiology of the syndrome; describes its diagnosis, clinical course, and treatment; and exemplifies the syndrome with a case study.

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Related Concepts

Psychogenic Coma
Hemodynamics
Inappropriate ADH Syndrome
Nephrons
Osmolality
Non-epileptic Convulsion
Precipitating Factors
Nursing, Perinatal

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