Sialendoscopic management of autoimmune sialadenitis: a review of literature

Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
A GalloM De Vincentiis

Abstract

Autoimmune diseases of major salivary glands include Sjögren's syndrome and a complex of disorders classified as immunoglobulin G4-related diseases. These pathologies are characterised by an autoimmune reaction mediated by T-helper lymphocytes that targets the ducts of exocrine glands in Sjögren's syndrome and glandular parenchyma in immunoglobulin G4-related diseases. Immunoglobulin G4-related diseases represent recently introduced multi-organ diseases that also involve the salivary glands. However, the morbid conditions once known as Mikulicz's disease and Kuttner's tumour were recently considered as two variants of immunoglobulin G4-related diseases affecting the major salivary glands ( immunoglobulin G4-related sialadenitis). This review briefly summarises the pathogenesis and clinical features of autoimmune diseases of the major salivary glands, focusing on the diagnostic and therapeutic role of sialendoscopy.

Citations

Aug 3, 2019·International Journal of Pediatric Otorhinolaryngology·Romain AmbrosinoNicolas Graillon
Apr 16, 2021·American Journal of Ophthalmology·Sandra Lora CremersAlberto Martinez
May 25, 2021·Otolaryngologic Clinics of North America·S Andrew Skillington, M Allison Ogden
Jul 9, 2021·The Laryngoscope·Samanta BuchholzerFrancis Marchal
Nov 2, 2021·Acta Dermato-venereologica·Jurand DomańskiJacek C Szepietowski

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Methods Mentioned

BETA
biopsy
ESR
imaging techniques
lavage

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Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

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