Abstract
Obesity and hypertension are closely associated risk factors for cardiovascular disease. An increase in body mass index is commonly associated with an increase in blood pressure and weight reduction is recommended as the principal intervention in the obese hypertensive patient. Sibutramine therapy, as part of a programme of diet and exercise, can help achieve marked weight reduction and improve metabolic and other cardiovascular risk factors. In hypertensive patients, weight loss induced by sibutramine has also been found to reduce blood pressure. Studies have shown that in the obese, well-controlled hypertensive patient, sibutramine is a safe and well-tolerated therapy offering the many clinical benefits associated with weight reduction in this high-risk population.
Citations
Jun 10, 2005·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·William G Haynes, Zoltan Egri
Aug 14, 2003·Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society·A M Sharma
Jun 4, 2010·Diabetes, Obesity & Metabolism·S Colagiuri
Aug 10, 2007·International Journal of Clinical Practice·M Lean, A Mullan
Jan 1, 2007·Obesity Research & Clinical Practice·Gary WittertNick Finer
Aug 16, 2005·Sleep Medicine·Denis Martinez, Bibiana Ribeiro Basile
Oct 22, 2003·Primary Care·Donna H Ryan
Apr 25, 2006·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·K Narkiewicz
May 21, 2005·Journal of Human Hypertension·Z Gaciong, G Placha
Nov 24, 2007·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·M FlorentinM S Elisaf
Jul 16, 2008·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Tunay SentürkIbrahim Baran
Dec 5, 2002·The Journal of School Nursing : the Official Publication of the National Association of School Nurses·Randall M Peterson
Mar 15, 2006·Annual Review of Public Health·Patricia Dolan Mullen, Gilbert Ramírez
Aug 2, 2008·Expert Opinion on Pharmacotherapy·Bikash Sharma, David C Henderson
Nov 28, 2002·Eating and Weight Disorders : EWD·O BoselloC M Rotella