PMID: 11605165Oct 18, 2001Paper

Sickle cell disease: current clinical management

Seminars in Hematology
Samir K Ballas

Abstract

The phenotypic expression of sickle cell disease (SCD) varies greatly among patients and longitudinally in the same patient. The phenotype influences all aspects of the life of affected individuals including social interactions, intimate relationships, family relations, education, employment, and spirituality. The clinical, manifestations of SCD are protean and fall into three major categories: (1) anemia and its sequelae; (2) pain and related issues; and (3) end-organ failure including infection. This review will emphasize the pathophysiology and management of sickle cell pain, as well as organ failure and its management.

Citations

May 22, 2010·Advances in Hematology·Radha RaghupathyJane A Little
Apr 6, 2004·Journal of Vascular and Interventional Radiology : JVIR·Steven C WagnerKevin L Sullivan
Feb 22, 2012·Journal of Infection and Public Health·Salam AlkindiAnil Pathare
Jun 17, 2009·Journal of the American Academy of Nurse Practitioners·Valerie Mann-Jiles, Diana Lynn Morris
May 27, 2015·Pain Practice : the Official Journal of World Institute of Pain·Lucia De FranceschiGabriele Finco
Sep 17, 2013·Pediatric Blood & Cancer·Clarisse Lopes de Castro LoboSilvia Maia Farias de Carvalho
Oct 20, 2004·Advances in Skin & Wound Care·Jennifer T Trent, Robert S Kirsner
Nov 25, 2006·Hematology·Paul S Swerdlow
Sep 17, 2010·Acta Physiologica Hungarica·D M Bolarin, E C Azinge
Mar 29, 2003·Paediatric Drugs·Jennifer Stinson, Basem Naser

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