Sickle cell morbidity profile in Omani children

Annals of Tropical Paediatrics
F JaiyesimiN Krishnamoorthy

Abstract

In order to define the morbidity profile of sickle cell disease in Omani children, we analysed data on 97 children (53 boys, 44 girls) aged < or = 12 years admitted under our care in a regional referral hospital between July 1999 and June 2000. Ninety of them had sickle cell anaemia (HbSS disease) and seven had sickle cell thalassaemia (beta zero). Their mean (SD) steady-state Hb was 7.9 (1.2), range 6-10 g/dl. They were admitted on 316 occasions during the 12-month period. The number of admissions per child ranged from one to 12 (mean 3.3). Vaso-occlusive crises were the main reason for admission (83%), followed by severe anaemia (12%) and infections (4%). During the study period, 31% received blood transfusions. Weight faltering was very common, 68% falling below the 5th percentile of the National Center for Health Statistics reference curves compared with 28% of age- and sex-matched non-sicklers (p < 0.001). Other complications included hypersplenism (four), ischaemic necrosis of the femoral head (two), and one case each of acute chest syndrome, acute splenic sequestration, cholelithiasis and pathological fracture of a lumbar vertebra. Overall, 71% of the children had moderately severe or severe disease. This pattern seems t...Continue Reading

References

Mar 1, 1979·The American Journal of Clinical Nutrition·P V HamillW M Moore
Jan 1, 1978·Annals of Internal Medicine·R P PerrineF Shoup
Jul 4, 1991·The New England Journal of Medicine·O S PlattT R Kinney
Sep 1, 1991·British Journal of Haematology·M A PadmosG R Serjeant
Jan 1, 1991·Annals of Tropical Paediatrics·N BashirL Sharif
Aug 1, 1990·Journal of Tropical Pediatrics·M A el-HazmiA S Warsy
Jan 1, 1989·Annals of the New York Academy of Sciences·O O Akinyanju
Apr 1, 1983·Journal of Tropical Pediatrics·W N Kaine
Jan 1, 1980·Transactions of the Royal Society of Tropical Medicine and Hygiene·A S Ibrahim
Jul 1, 1994·British Journal of Haematology·G R SerjeantP W Thomas
Jan 1, 1996·British Journal of Haematology·G SerjeantP Thomas
Jun 1, 1996·Pediatric Clinics of North America·P A Lane
Oct 1, 1996·Community Dentistry and Oral Epidemiology·M Al-IsmailyM Knight
Oct 1, 1996·The Journal of Obstetrics and Gynaecology Research·K TalafihS Jaradat
Mar 1, 1995·Current Opinion in Hematology·G R Serjeant
Apr 1, 1999·The New England Journal of Medicine·M H Steinberg
May 8, 1992·Current Opinion in Ophthalmology·A D Penman, G R Serjeant
May 20, 1999·Archives of Disease in Childhood·S A MagnusG R Serjeant
Feb 24, 2000·Archives of Disease in Childhood·P W ThomasG R Serjeant

❮ Previous
Next ❯

Citations

Aug 30, 2008·Annals of Tropical Paediatrics·A-W M Al-SaqladiB J Brabin
Dec 2, 2010·Annals of Tropical Paediatrics·A-W M Al-SaqladiB J Brabin
Sep 6, 2012·European Journal of Pediatrics·Carmen GarridoJorge Huerta
Sep 17, 2004·Ophthalmic Epidemiology·Rajiv KhandekarJawad Al Lawati
Aug 25, 2007·Annals of Tropical Paediatrics·Olufemi Jaiyesimi, Mohamed Kasem
May 20, 2014·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·C Garrido ColinoE Cela de Julián
Sep 11, 2020·Anemia·Abdul-Wahab M Al-SaqladiAida H Al-Sadeeq
Mar 10, 2020·Complementary Therapies in Medicine·Samir K Ballas, Deepika S Darbari

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Related Papers

Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition
E B FungVirginia A Stallings
Tijdschrift voor ziekenverpleging
P C Stuiver
International Journal of Cosmetic Science
Journal of the American Dietetic Association
B M MalinauskasVirginia A Stallings
© 2022 Meta ULC. All rights reserved