Sifting the wheat from the chaff? Evidence for the existence of an asymmetric fibromyalgia phenotype.

European Journal of Pain : EJP
Helena H KaziyamaDaniel Ciampi de Andrade

Abstract

The different phenotypic presentations of fibromyalgia (FM) have been infrequently studied and may have diagnostic and therapeutic implications. The aim of this study was to explore differences between FM patients with classical symmetric (s-FM) presentation and FM patients with marked asymmetric (a-FM) pain. We performed two consecutive cross-sectional studies on FM patients and matched healthy volunteers (HV). FM patients were divided into a-FM (and s-FM groups according to their score of pain intensity on each body side; patients with a difference of ≥40 mm in VAS between left and right sides were classified as a-FM, otherwise classified as s-FM. Participants (FM = 32; HV = 31) were assessed for clinical, cortical excitability (CE), quantitative sensory testing (QST; study 1), and intraepidermal nerve fibre density (IENFD) determinations (study 2). While pain intensity did not significantly differ between s-FM and a-FM patients, pain interference in daily activities was significantly higher in the a-FM as compared to the s-FM group (54.7 ± 8.9 and 37.6 ± 13.5; p < .0001). PPT was significantly lower in the more painful side of a-FM as compared to the HV (27.7 ± 7.9 and 49.9 ± 13.0; p < .0001), while PPT in the less painful s...Continue Reading

References

Dec 1, 1992·Electroencephalography and Clinical Neurophysiology·J Valls-SoléM Hallett
Sep 1, 1992·Brain and Cognition·R J Davidson
Jul 1, 1989·The British Journal of Psychiatry : the Journal of Mental Science·S E StarksteinT R Price
Jul 1, 1988·Pain·Eldon TunksSue Kalaher
Jun 1, 1983·Acta Psychiatrica Scandinavica·A S Zigmond, R P Snaith
Aug 1, 1993·Electroencephalography and Clinical Neurophysiology·T KujiraiL G Cohen
Aug 1, 1996·Electroencephalography and Clinical Neurophysiology·H TokimuraJ C Rothwell
Dec 7, 2007·The Journal of Pain : Official Journal of the American Pain Society·Robert H DworkinStojan Zavisic
Feb 1, 2007·Revista brasileira de anestesiologia·José Alvaro Marques MarcolinoLuís Augusto Cunha Alli
May 30, 2009·Arthritis and Rheumatism·Frederick Wolfe
Mar 12, 2010·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Karine A FerreiraCharles S Cleeland
Nov 3, 2010·Journal of the Peripheral Nervous System : JPNS·Giuseppe LauriaIngemar S J Merkies
Sep 14, 2011·Arthritis and Rheumatism·Bradley R FoersterRichard E Harris
Aug 30, 2012·Nature Methods·Caroline A SchneiderKevin W Eliceiri
Feb 5, 2013·Rheumatology International·Luciana Alvarenga da SilvaSilvia Regina Dowgan Tesseroli de Siqueira
Mar 12, 2013·Brain : a Journal of Neurology·Nurcan ÜçeylerClaudia Sommer
Dec 10, 2013·Pain Management Nursing : Official Journal of the American Society of Pain Management Nurses·Karine Azevedo São Leão FerreiraManoel Jacobsen Teixeira
Jan 23, 2014·Arthritis & Rheumatology·Marco L LoggiaVitaly Napadow
Apr 12, 2014·Rheumatology International·Yolanda TriñanesMaría T Carrillo-de-la-Peña
Nov 21, 2014·The Clinical Journal of Pain·Mark P JensenJon D Howe
Jun 17, 2015·Scandinavian Journal of Rheumatology·N EgloffS Stauber
Oct 23, 2015·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Franz RiedererPeter S Sándor
Mar 5, 2016·European Journal of Pain : EJP·R BaronR-D Treede
Mar 24, 2016·Scientific Reports·Linda OudejansMonique van Velzen
Sep 26, 2017·The Journal of Pain : Official Journal of the American Pain Society·Winfried HäuserMary-Ann Fitzcharles

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Citations

Mar 20, 2021·European Journal of Pain : EJP·Clarice ListikDaniel Ciampi de Andrade

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