SIGNAL blood culture system for detection of bacteremia in neonates.

Journal of Clinical Microbiology
C Trombley, J D Anderson

Abstract

In the SIGNAL (Oxoid Ltd., Basingstoke, United Kingdom) blood culture system, gas produced by bacterial metabolism displaces medium from the culture bottle into an upper reservoir via a hollow needle. Displacement of media may provide a visual indication of the presence of both aerobic and anaerobic organisms in a single medium. The single-bottle SIGNAL system was compared with paired BACTEC 16B and 7D (Johnston Laboratories, Inc., Towson, Md.) radiometric system bottles by using bacterial inocula and conditions which simulated those found in neonatal and pediatric populations. The single SIGNAL bottle was a good as the combined BACTEC media for Escherichia coli and Staphylococcus aureus, but was slower for Candida spp., Haemophilus influenzae, Pseudomonas aeruginosa, Staphylococcus epidermidis, group B streptococci, alpha-streptococci, and pneumococci. The SIGNAL system failed to detect four of five isolates of Neisseria meningitidis and four of eight anaerobic organisms. The SIGNAL system is not suitable for neonatal blood cultures at its present state of development.

References

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Citations

Sep 1, 1989·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A Telenti, G D Roberts
Apr 1, 1993·The Journal of Applied Bacteriology·M StevensA Donkin
Sep 1, 1989·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J M Campos
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Dec 1, 1988·Journal of Clinical Microbiology·P R MurrayJ E Hoppe-Bauer
Jan 1, 1990·Clinical Microbiology Reviews·J M Jones
Jun 1, 1989·Journal of Clinical Microbiology·C A HimmelreichG A Storch
Apr 1, 1989·Journal of Clinical Microbiology·J D AndersonN Cimolai

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