PMID: 11926317Apr 3, 2002Paper

Signaling and cell death in lymphocytes

Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]
Richard A FlavellR J Davis

Abstract

After activation, CD4 helper T (Th) cells differentiate into Th1 or Th2 effector cells. These two subsets produce distinct profiles of cytokines and regulate different immune responses. Here we discuss transcription factors and signaling pathways that are selectively expressed or activated in Th1 and Th2 cells to regulate cytokine gene expression, cell proliferation and apoptosis.

References

Nov 17, 1998·The Journal of Experimental Medicine·M RincónR A Flavell
Dec 16, 1998·Science·C DongR A Flavell
Jan 6, 2000·The Journal of Experimental Medicine·L WeissR A Flavell

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Citations

Jul 17, 2003·Journal of Neuroimmunology·Taekyun ShinEui-Ju Yeo
Nov 17, 2005·The Journal of Experimental Medicine·Lin LiuBinfeng Lu
Aug 26, 2010·Journal of Immunotoxicology·Valentina GalbiatiEmanuela Corsini
Oct 30, 2008·Journal of Immunotoxicology·Alessandra GennariLaura Gribaldo
Aug 22, 2008·Biomedical and Environmental Sciences : BES·Long-Guo YuanQi-Yang He
Sep 22, 2010·Multiple Sclerosis : Clinical and Laboratory Research·Chiara FerrandiPaola F Zaratin
Feb 10, 2007·Journal of Leukocyte Biology·Konstantin Salojin, Tamas Oravecz
Apr 25, 2008·Current Protocols in Immunology·Alan J Whitmarsh, Roger J Davis
Oct 8, 2009·Alternatives to Laboratory Animals : ATLA·Emanuela Corsini, Erwin L Roggen

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Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis