Signaling by neuronal tyrosine kinase receptors: relevance for development and regeneration

The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology
B HausottL Klimaschewski

Abstract

Receptor tyrosine kinase activation by binding of neurotrophic factors determines neuronal morphology and identity, migration of neurons to appropriate destinations, and integration into functional neural circuits as well as synapse formation with appropriate targets at the right time and at the right place. This review summarizes the most important aspects of intraneuronal signaling mechanisms and induced gene expression changes that underlie morphological and neurochemical consequences of receptor tyrosine kinase activation in central and peripheral neurons.

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Citations

Mar 12, 2013·Cellular and Molecular Life Sciences : CMLS·Ina M Wittko-SchneiderKarl H Plate
May 13, 2011·Cell and Tissue Research·Kerstin I Mehnert, Rafael Cantera
Apr 22, 2011·Journal of Biochemistry·Ania Dabrowski, Hisashi Umemori
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Nov 28, 2009·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Roland Pochet, Jean-Pierre Timmermans

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