Mar 19, 1999

Signaling of cell fate decisions by CLAVATA3 in Arabidopsis shoot meristems

Science
J C FletcherElliot M Meyerowitz

Abstract

In higher plants, organogenesis occurs continuously from self-renewing apical meristems. Arabidopsis thaliana plants with loss-of-function mutations in the CLAVATA (CLV1, 2, and 3) genes have enlarged meristems and generate extra floral organs. Genetic analysis indicates that CLV1, which encodes a receptor kinase, acts with CLV3 to control the balance between meristem cell proliferation and differentiation. CLV3 encodes a small, predicted extracellular protein. CLV3 acts nonautonomously in meristems and is expressed at the meristem surface overlying the CLV1 domain. These proteins may act as a ligand-receptor pair in a signal transduction pathway, coordinating growth between adjacent meristematic regions.

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Mentioned in this Paper

CLV1 protein, Arabidopsis
Genes, Plant
Cell Fate
Chimeric Proteins, Recombinant
Arabidopsis
Meristem
Genetic Analysis
Genetic Screening Method
Signal Transduction Pathways
Gene Expression Regulation, Plant

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