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Significance analysis of microarrays applied to the ionizing radiation response

Proceedings of the National Academy of Sciences of the United States of America

Apr 20, 2001

V G TusherG Chu

Abstract

Microarrays can measure the expression of thousands of genes to identify changes in expression between different biological states. Methods are needed to determine the significance of these changes while accounting for the enormous number of genes. We describe a method, Significance Ana...read more

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Apoptosis, Intrinsic Pathway
Transcription, Genetic
Base Excision Repair
Receptor Down-Regulation
Gene Expression
Nucleotide Excision Repair Pathway
Nucleotide Excision Repair
Apoptosis
Cell Cycle
4
2537
2
Paper Details
References
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12
  • References19
  • Citations6402
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Significance analysis of microarrays applied to the ionizing radiation response

Proceedings of the National Academy of Sciences of the United States of America

Apr 20, 2001

V G TusherG Chu

PMID: 11309499

DOI: 10.1073/pnas.091062498

Abstract

Microarrays can measure the expression of thousands of genes to identify changes in expression between different biological states. Methods are needed to determine the significance of these changes while accounting for the enormous number of genes. We describe a method, Significance Ana...read more

Mentioned in this Paper

Biochemical Pathway
Apoptosis, Intrinsic Pathway
Transcription, Genetic
Base Excision Repair
Receptor Down-Regulation
Gene Expression
Nucleotide Excision Repair Pathway
Nucleotide Excision Repair
Apoptosis
Cell Cycle
4
2537
2

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Mammalian Cell Cycle & Cell Growth Control

Mammalian cell cycle is a complex process regulated by several signal transduction pathways and enzymes. Here is the latest research on regulation of mammalian cell cycle and growth.

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Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

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Cluster analysis and display of genome-wide expression patterns

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Paper Details
References
  • References19
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12
  • References19
  • Citations6402
12345...
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