PMID: 8587000Jan 1, 1995Paper

Significance of aneuploidy in non-Hodgkin lymphomas

Journal of Clinical Laboratory Analysis
J VuckovićM Dubravcić

Abstract

The incidence of aneuploidy was determined by flow cytometric analysis in paraffin-embedded tumor samples of 125 patients with non-Hodgkin lymphoma (NHL). There were 48 low-grade (LG) and 77 high-grade (HG) tumors. Aneuploidy was found in 34 (27%) NHL, 15 (31%) LG, and 19 (25%) HG tumors. The analysis of patient survival showed a significantly better survival of patients with LG than HG NHL, but the presence of aneuploidy did not influence the survival on the level of all patients, patients with LG or patients with HG NHL. In patients with LG NHL a tendency of diploid vs. aneuploid patients to survive longer was observed, but only at P = 0.056 significance level.

References

Jul 1, 1977·Beiträge Zur Pathologie·W Sandritter, H Grimm
Mar 1, 1977·Journal of the National Cancer Institute·R SilvestriniF Rilke
Mar 1, 1990·American Journal of Clinical Pathology·T W BauerH S Levin
Oct 1, 1986·British Journal of Cancer·D R MorganC C Bird
Oct 1, 1985·Journal of Clinical Pathology·R S Camplejohn, J C Macartney
Nov 1, 1983·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·D W HedleyE A Musgrove
Dec 1, 1980·The Journal of Clinical Investigation·S E ShackneyR J Lukes
Jan 1, 1981·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J H Scarffe, D Crowther

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Citations

Feb 18, 2003·British Journal of Haematology·Mitchell S CairoJonathan L Finlay

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