Significance of body mass index for diagnosing sarcopenia is equivalent to slow gait speed in Japanese individuals with type 2 diabetes: Cross-sectional study using outpatient clinical data.

Journal of Diabetes Investigation
Shuhei NakanishiHideaki Kaneto

Abstract

This study examined the association between body mass index (BMI) and the risk of sarcopenia in Japanese type 2 diabetes patients. Patients with type 2 diabetes who visited an outpatient clinic comprised the study's participants. Sarcopenia was defined using the definition of the Asian Working Group for Sarcopenia 2014. The area under the curve was examined for the presence of sarcopenia based on the receiver operating characteristic curve of BMI. Among 1,137 patients, 210 were diagnosed with low grip strength, 78 with slow gait speed, 444 with low muscle mass and 142 with sarcopenia. The optimal cut-off point of BMI level for risk of sarcopenia was 24.4 kg/m2 (area under the curve 0.729, 95% confidence interval 0.688-0.770, sensitivity 0.587, specificity 0.789). Furthermore, the receiver operating characteristic curve of BMI for sarcopenia did not significantly differ (P = 0.09) from that of gait speed, an established marker of sarcopenia. In both the male and female groups, there was no difference between the receiver operating characteristic curves of BMI and gait speed for sarcopenia. (P = 0.23 and P = 0.40, respectively). These results suggest that a BMI <24 kg/m2 among Japanese patients with type 2 diabetes could increase...Continue Reading

References

Jun 10, 2004·Journal of Physiological Anthropology and Applied Human Science·Shinichi DemuraTamotsu Kitabayashi
Nov 10, 2007·The American Journal of Clinical Nutrition·S Goya WannametheePeter H Whincup
Jan 15, 2010·Journal of the American Geriatrics Society·Seung Seok HanHo Jun Chin
Feb 2, 2010·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Francesco LandiGraziano Onder
Jun 16, 2010·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Hanneke A H WijnhovenMarjolein Visser
May 11, 2011·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Carolina H Y LingAndrea B Maier
Nov 14, 2013·Journal of the American Pharmacists Association : JAPhA
Jan 28, 2014·Journal of the American Medical Directors Association·Liang-Kung ChenHidenori Arai
Sep 10, 2014·The Journal of Clinical Endocrinology and Metabolism·Shiro TanakaUNKNOWN Japan Diabetes Complications Study Group and the Japanese Elderly Diabetes Intervention Trial Group
Dec 10, 2016·Journal of Diabetes Investigation·Eiichi ArakiTakashi Kadowaki
Aug 2, 2018·Physiological Reviews·Max C Petersen, Gerald I Shulman
Aug 3, 2019·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Jakub MesinovicDavid Scott
Oct 12, 2019·JAMA Network Open·Line Jee Hartmann RasmussenTerrie E Moffitt

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Software Mentioned

JMP
EZR
R Commander
R

Related Concepts

Related Feeds

Biomarkers for Type 2 Diabetes

Biomarkers can help understand chronic diseases and assist in risk prediction for prevention and early detection of diseases. Here is the latest research on biomarkers in type 2 diabetes, a disease in which the body is unable to produce or properly use insulin.

Related Papers

BMJ : British Medical Journal
Avan Aihie Sayer
Clinical Medicine : Journal of the Royal College of Physicians of London
Alfonso J Cruz-Jentoft, Francesco Landi
La Revue du praticien
Anne-Sophie Boureau, Laure de Decker
© 2021 Meta ULC. All rights reserved