Significance of chronic epilepsy in glial tumors and correlation with surgical strategies

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
Ok-Joon KimByung-In Lee

Abstract

This study was designed to compare the frequency of postoperative epilepsy in patients with acute and chronic pre-operative epilepsy and with frontal or temporal lobe glial tumors based on the hypothesis that patients with chronic epilepsy do worse. We compared the clinical and diagnostic characteristics of the patients (n = 73) who had seizures preoperatively with those of the patients (n = 153) who did not. Among those who have had seizures preoperatively, we compared those (n = 32, chronic seizure group) who had seizures a year or more prior to surgery with those (n = 41, acute seizure group) who had seizures less than a year prior to surgery. Among the various factors, the frequency of benign pathology and favorable neurological state were higher in the seizure group than in the non-seizure group (p < 0.05). Complex partial seizures and low-grade tumors were frequent in the chronic seizure group, whereas simple partial seizures and high-grade tumors were frequent in the acute seizure group. Seizure-free rate was significantly higher in the acute seizure group than in the chronic group (p < 0.05). Also, the difference of seizure control rate between surgical strategies was statistically significant (p < 0.05). This study ind...Continue Reading

References

Oct 1, 1991·Journal of Neurology, Neurosurgery, and Psychiatry·D F SmithD W Chadwick
Jan 1, 1990·Acta Neuropathologica·J H KimD D Spencer
Jan 1, 1990·Acta neurochirurgica·S FranceschettiG Avanzini
Apr 1, 1989·Journal of Neurosurgery·J F HirschE Hoppe-Hirsch
Apr 1, 1985·Archives of Neurology·F Morrell
Apr 1, 1984·Neurology·D D SpencerP D Williamson
Jul 1, 1995·Archives of Neurology·P L MootsB Abou-Khalil

❮ Previous
Next ❯

Citations

Jun 27, 2007·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Joong-Uhn Choi
Mar 24, 2012·Neurosurgery Clinics of North America·Dario J EnglotPaul A Garcia
Sep 29, 2009·Epilepsy Research·Roberto GaggeroPasquale Striano
Jan 15, 2017·Experimental and Molecular Pathology·Cheng HuangJin-Mei Li
May 29, 2008·Expert Review of Neurotherapeutics·Christian BrognaHugues Duffau
Jun 10, 2011·Expert Review of Neurotherapeutics·Devender BhallaPierre-Marie Preux
Nov 28, 2017·Journal of Neuro-oncology·Andrés F CardonaZyanya Lucia Zatarain-Barrón
Aug 4, 2021·World Neurosurgery·Joshua PepperErminia Albanese

❮ Previous
Next ❯

Related Concepts

Related Feeds

Astrocytes

Astrocytes are glial cells that support the blood-brain barrier, facilitate neurotransmission, provide nutrients to neurons, and help repair damaged nervous tissues. Here is the latest research.