Significance of FDG-PET in Identification of Diseases of the Appendix - Based on Experience of Two Cases Falsely Positive for FDG Accumulation.

Case Reports in Gastroenterology
Shimpei OgawaShingo Kameoka

Abstract

A discussion of the significance of F-fluorodeoxyglucose positron emission tomography (FDG-PET) in the identification of diseases of the appendix is presented based on two cases falsely positive for FDG accumulation. Both cases were palpable for a tumor in the lower right abdominal region and a prominently enlarged appendix was depicted by CT. Although the patients underwent ileocecal resection based on a strong suspicion of appendiceal cancer rather than appendicitis since abnormal accumulation exhibiting maximum standard uptake values (SUVs) of 7.27 and 17.11, respectively, was observed at the same site in FDG-PET examination and since there no malignant findings observed histologically, the patients were diagnosed with appendicitis. Although FDG specifically accumulates not only in malignant tumors, but also in diseases such as acute or chronic inflammation, abscesses and lymphadenitis, and identification based on SUVs has been reported to be used as a method of identification, the two cases reported here were both false-positive cases exhibiting high maximum SUVs. At the present time, although the significance of FDG-PET in the identification of diseases of the appendix is somewhat low and there are limitations on its appli...Continue Reading

Citations

Sep 6, 2011·Clinical Nuclear Medicine·Xinchong ShiZhifeng Chen
Feb 10, 2012·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Kwang Dae HongHong Young Moon
Nov 30, 2013·Pediatric Radiology·Hamilton E ReaveyStephen F Simoneaux
Dec 1, 2012·Nuclear Medicine and Molecular Imaging·Duck-Soo ChungJae-Bok Park
Jul 18, 2014·PET Clinics·Andres Kohan, Norbert E Avril
Jan 1, 2013·Case Reports in Gastroenterology·Noriaki KoizumiEigo Otsuji
Jul 19, 2017·Clinical Nuclear Medicine·Syed Zama AliLi Mei Poon
Jan 18, 2019·Annals of Nuclear Medicine·Christopher SilmanKenichiro Otsuka

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