PMID: 8955329Dec 1, 1996Paper

Significance of HPr in catabolite repression of alpha-amylase

Journal of Bacteriology
M I Voskuil, G H Chambliss

Abstract

CcpA and HPr are presently the only two proteins implicated in Bacillus subtilis global carbon source catabolite repression, and the ptsH1 mutation in the gene for the HPr protein was reported to relieve catabolite repression of several genes. However, alpha-amylase synthesis by B. subtilis SA003 containing the ptsH1 mutation was repressed by glucose. Our results suggest HPr(Ser-P) may be involved in but is not required for catabolite repression of alpha-amylase, indicating that HPr(Ser-P) is not the sole signaling molecule for CcpA-mediated catabolite repression in B. subtilis.

References

Sep 1, 1965·Proceedings of the National Academy of Sciences of the United States of America·P SchaefferJ P Aubert
Dec 1, 1995·Journal of Bacteriology·I Martin-VerstraeteG Rapoport

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Citations

Aug 5, 1998·Proceedings of the National Academy of Sciences of the United States of America·J H KimG H Chambliss
Oct 6, 2000·Annual Review of Microbiology·J Stülke, W Hillen
May 27, 2005·Molecular Microbiology·Robert P Shivers, Abraham L Sonenshein
Dec 13, 2006·Microbiology and Molecular Biology Reviews : MMBR·Josef DeutscherPieter W Postma
Mar 5, 2009·Microbiology and Molecular Biology Reviews : MMBR·Ana Gutiérrez-PreciadoEnrique Merino
Apr 16, 1998·Microbiology·David Foulger, Jeffery Errington
Jun 8, 2002·Journal of Molecular Biology·Lwin Mar Aung-HilbrichWolfgang Hillen
Nov 14, 1997·Journal of Bacteriology·V MonederoG Pérez-Martínez
Nov 26, 1998·Journal of Bacteriology·X Liu, H W Taber

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