Significance of post-pacing intervals shorter than tachycardia cycle length for successful catheter ablation of atypical flutter.

Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Pietro Bernardo Dall'AglioDipen C Shah

Abstract

During entrainment mapping of macro-reentrant tachycardias, the time difference (dPPI) between post-pacing interval (PPI) and tachycardia cycle length (TCL) is thought to be a function of the distance of the pacing site to the re-entry circuit and dPPI < 30 ms is considered within the re-entry circuit. This study assessed the importance of PPI < TCL as a successful target for atypical flutter ablation. A total of 177 ablation procedures were investigated. Surface electrocardiograms (ECGs) were evaluated and combined activation and entrainment mapping were performed to choose ablation sites. Each entrainment sequence immediately preceding static radiofrequency delivery at the same site was analysed. A total of 545 entrainment sequences were analysed. dPPI < 0 ms was observed in 45.3% (247/545) sequences. Ablation resulted in tachycardia termination more often at sites with dPPI < 0 (27.8% vs. 14.5%, P < 0.001) and with a progressively increasingly inverse correlation between dPPI duration and ablation success [odds ratio (OR): 0.974; 95% confidence interval (CI) 0.960-0.988; P < 0.001]. Tachycardia termination or cycle length prolongation also occurred more often at sites with dPPI < 0 (50.6% vs. 33.2%, P < 0.001) and with a sim...Continue Reading

References

Mar 1, 1988·Journal of the American College of Cardiology·W G StevensonT Klitzner
Mar 1, 1995·Journal of Cardiovascular Electrophysiology·W G StevensonP L Friedman
Apr 13, 2001·Journal of the American College of Cardiology·K SoejimaP L Friedman
Oct 3, 2006·Journal of the American College of Cardiology·Oussama M WazniAndrea Natale
Feb 12, 2009·Journal of Cardiovascular Electrophysiology·Pierre JaïsMichel Haïssaguerre
Feb 12, 2009·Journal of Cardiovascular Electrophysiology·Rajat Deo, Ronald Berger
Nov 11, 2016·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Roger A WinkleRob A Patrawala
Apr 15, 2017·Circulation. Arrhythmia and Electrophysiology·Roderick Tung
Jul 19, 2017·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Pasquale Santangeli, Sanjay Dixit
Sep 19, 2019·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Teresa StrisciuglioSebastien Knecht

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