Sep 1, 1975

Significance of serum lipoproteid-X (LP-X) determination for the diagnosis of cholestasis in chronic liver diseases

Polish Medical Sciences and History Bulletin
B Milewski, Z Palynyczko

Abstract

Among 179 patients with various chronic diseases of the liver the authors found in 20 cases histological evidence of intrahepatic cholestasis and in all these cases lipoproteid X (LP-X) was present in the serum. In the group of 159 patients without evidence of cholestasis in microscopic examination of liver tissue LP-X was demonstrated only in two cases (1.3%). The results of investigations confirm the view that detection of LP-X in the serum is a specific and sensitive index of cholestasis and its value in the diagnosis of this condition is greater than that of determinations of alkaline phosphatase, gamma-glutamyl-transpeptidase, leucinamino-peptidase activity or cholesterol in the serum.

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Mentioned in this Paper

Clinical Enzyme Tests (Procedure)
Chronic Disease
Alkaline Phosphatase Measurement
Alkaline Phosphatase
Intrahepatic Cholestasis
Liver Diseases
Cholestasis
Lipoproteins
Peptidyltransferase
Liver Dysfunction

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