PMID: 8946338Nov 6, 1996Paper

Significance of sympathetic skin response in the assessment of autonomic failure in patients with spinal cord injury

Journal of the Autonomic Nervous System
A CurtV Dietz

Abstract

As a result of spinal cord injury (SCI) descending spinal sympathetic pathways can be severed. Because of its clinical significance, the aim of this study was to assess the disturbance of the spinal sympathetic pathway by clinical and electrophysiological examinations. The sympathetic skin response (SSR) due to electrical stimulation of median nerve and transcranial magnetic stimulation was examined in 70 patients with complete and incomplete spinal cord injury. Clinical and neurological examinations were performed in these patients according to the protocol of the American Spinal Injury Association (ASIA). The SSR can be used to assess the integrity of the spinal sympathetic nervous system. In patients with complete tetraplegia and paraplegics with high thoracical lesions (up to level T3) SSRs of the hands and feet were absent. In patients with complete paraplegia and thoroacic lesions from level T4 up to T8 the SSRs could be evoked in the hands but not in the feet. However, in paraplegics with lumbal and thoracic lesions below level T8 SSRs of the hands and feet could be recorded. In about 50% of the patients with clinically incomplete SCI lesions SSR potentials were abolished, indicating that the spinal sympathetic system wa...Continue Reading

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Citations

Nov 3, 2006·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Elisabeth ChroniVassiliki Sirrou
Jul 29, 2011·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Jean G PrevinairePierre Denys
Mar 1, 2011·Archives of Physical Medicine and Rehabilitation·Steven KirshblumAmitabh Jha
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Jul 25, 2000·BJU International·D De Ridder, L Baert

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