Significance of the EEG and epileptiform abnormalities in antiepileptic drug discontinuance

Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society
Jeffrey W Britton

Abstract

The question of the advisability of antiepileptic drug (AED) discontinuance is common in epilepsy care. With currently available therapies, prolonged periods of seizure remission are not uncommon. After a prolonged period of seizure freedom, patients and clinicians often begin to wonder whether therapy can be discontinued. The AED discontinuance literature shows relapse rates ranging from 20% to 60%. Factors with prognostic significance have been recognized, including several findings identified on the routine EEG. This article reviews the role of EEG in the setting of AED discontinuance and summarizes the literature describing the prognostic value of EEG.

References

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Citations

May 25, 2012·Seizure : the Journal of the British Epilepsy Association·Milen PavlovićTatjana Pekmezović
Apr 30, 2013·Seizure : the Journal of the British Epilepsy Association·Jessica Askamp, Michel J A M van Putten

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