Significance of the impact of motion compensation on the variability of PET image features

Physics in Medicine and Biology
M CarlesL Martí-Bonmatí

Abstract

In lung cancer, quantification by positron emission tomography/computed tomography (PET/CT) imaging presents challenges due to respiratory movement. Our primary aim was to study the impact of motion compensation implied by retrospectively gated (4D)-PET/CT on the variability of PET quantitative parameters. Its significance was evaluated by comparison with the variability due to (i) the voxel size in image reconstruction and (ii) the voxel size in image post-resampling. The method employed for feature extraction was chosen based on the analysis of (i) the effect of discretization of the standardized uptake value (SUV) on complementarity between texture features (TF) and conventional indices, (ii) the impact of the segmentation method on the variability of image features, and (iii) the variability of image features across the time-frame of 4D-PET. Thirty-one PET-features were involved. Three SUV discretization methods were applied: a constant width (SUV resolution) of the resampling bin (method RW), a constant number of bins (method RN) and RN on the image obtained after histogram equalization (method EqRN). The segmentation approaches evaluated were 40[Formula: see text] of SUVmax and the contrast oriented algorithm (COA). Param...Continue Reading

References

Oct 27, 2006·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Ursula NestleAnca-Ligia Grosu
May 22, 2007·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Angela van BaardwijkDirk De Ruysscher
Mar 4, 2008·International Journal of Radiation Oncology, Biology, Physics·Jochem W H WolthausEugène M F Damen
Dec 23, 2008·Physics in Medicine and Biology·S Surti, J S Karp
Sep 14, 2010·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Stacy J UyBicoMayil S Krishnam
Feb 16, 2011·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Florent TixierDimitris Visvikis
Oct 13, 2011·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Mathieu HattDimitris Visvikis
Nov 22, 2011·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Manushka VaidyaIssam El Naqa
Aug 18, 2012·Magnetic Resonance Imaging·Virendra KumarRobert J Gillies
Jul 17, 2013·European Journal of Nuclear Medicine and Molecular Imaging·Mathieu HattDimitris Visvikis
Feb 20, 2014·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Fanny OrlhacIrène Buvat
Dec 17, 2014·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Mathieu HattDimitris Visvikis
Jun 28, 2015·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Alin ChirindelUrsula Nestle
Aug 1, 2015·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Jianhua YanDavid Townsend
Aug 22, 2015·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Irene BuvatMichaël Soussan
Jun 9, 2016·European Journal of Nuclear Medicine and Molecular Imaging·Mathieu HattDimitris Visvikis
Nov 3, 2016·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Willem GrootjansEric P Visser
Jun 16, 2016·AJR. American Journal of Roentgenology·Usman BashirGary J Cook

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