Abstract
We evaluated dobutamine stress electrocardiography for detecting potentially reversible contractile dysfunction or residual ischemia in the infarct-related area. ST-T segment changes in pathologic Q wave leads during stress testing may reflect contractile reserve, inducible ischemia or passive mechanical stretching. Dobutamine echocardiography allows detection of contractile reserve at low doses and inducible ischemia at high doses. We used low (5 to 10 microg/kg body weight per min) and high doses (20 to 40 microg/kg per min) of dobutamine in 49 patients with a previous Q wave myocardial infarction and analyzed the relation between ST-T segment changes in pathologic Q wave leads and regional contraction. At low dose dobutamine, regional contraction improved in the infarct-related area in 23 patients. New or further ST segment elevation and pseudonormalization of negative T waves developed at low doses more frequently in patients with than without contractile reserve (both p < 0.001), giving a sensitivity of 43.5% and 60.9% and a specificity of 100% and 96.2%, respectively. At high dose dobutamine (43 patients), new or further ST segment elevation and pseudonormalization of negative T waves, occurring beyond those observed at l...Continue Reading
References
Apr 1, 1992·Journal of the American College of Cardiology·A MargonatoS L Chierchia
May 1, 1991·Circulation·S G SawadaH Feigenbaum
Apr 1, 1990·Journal of the American College of Cardiology·L A PiérardH E Kulbertus
Sep 1, 1990·Circulation·R A Kloner
Sep 1, 1990·Circulation·J RenkinJ Col
Feb 1, 1989·The American Journal of Cardiology·W E Boden, D H Spodick
Sep 1, 1989·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·N B SchillerI Schnittger
Apr 1, 1988·Circulation·R A BruceB R Chaitman
May 1, 1987·Journal of the American College of Cardiology·D E HainesR S Gibson
Jul 1, 1987·Circulation·A J BudaK P Gallagher
Oct 1, 1987·Circulation·K P GallagherA J Buda
Dec 1, 1987·American Heart Journal·J J MarinV N Udhoji
Jul 1, 1985·The American Journal of Cardiology·D TzivoniS Stern
Jan 1, 1972·Journal of Electrocardiology·K N Manvi, M H Ellestad
Jan 1, 1968·Monograph Series·G A Rose, H Blackburn
Oct 1, 1983·The American Journal of Cardiology·P ThérouxM G Bourassa
May 1, 1980·Circulation·R F DunnD T Kelly
Feb 1, 1995·Circulation·I AfridiW A Zoghbi
Apr 1, 1995·Journal of the American College of Cardiology·A MargonatoF Fazio
Mar 1, 1994·Journal of the American College of Cardiology·G La CannaO Visioli
May 1, 1994·The American Journal of Cardiology·M ArneseJ R Roelandt
Dec 16, 1993·The American Journal of Cardiology·M PrevitaliM Ferrario
Aug 1, 1993·Circulation·S C SmartH Feigenbaum
Aug 1, 1993·Circulation·C G CigarroaP A Grayburn
Citations
Feb 24, 2001·Clinical Cardiology·B A SamadM Jensen-Urstad
Oct 6, 2000·The American Journal of Cardiology·R RambaldiG Occhi
Mar 15, 1997·The American Journal of Cardiology·R RicciV Ceci
Jul 30, 1999·The American Journal of Cardiology·Y L HoP J Huang
Sep 11, 1999·The American Journal of Cardiology·F De FeliceG Borello
Mar 22, 2001·International Journal of Cardiology·V BodíA Llàcer
Jul 10, 2002·Journal of the American College of Cardiology·George HahalisAntonis S Manolis
Jul 21, 1998·Journal of the American College of Cardiology·G MobiliaR Buchberger
Mar 18, 1999·Journal of the American College of Cardiology·A NakanoT Ueda
Jun 11, 1999·Journal of the American College of Cardiology·R J GibbonsS C Smith
Jul 21, 1998·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·T WatanabeT Katagiri
Mar 10, 1999·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·A GiorgettiO Parodi
Aug 3, 2005·International Journal of Cardiology·Vicent BodíFrancisco J Chorro
Mar 1, 2006·American Heart Journal·Ana Lucia M ArrudaPatricia A Pellikka
Dec 30, 1999·The American Journal of Cardiology·A TamuraM Nasu
Apr 26, 2001·American Heart Journal·P LancellottiL A Piérard
Feb 27, 1999·American Heart Journal·L A PiérardH E Kulbertus
Jul 9, 2005·Journal of Electrocardiology·Jaume FiguerasJordi Soler Soler
May 16, 1998·Japanese Circulation Journal·R AjisakaY Sugishita
Nov 1, 2007·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Fabio InfusinoFilippo Crea
May 16, 2001·Coronary Artery Disease·A GiorgettiO Parodi
Aug 8, 2002·The Korean Journal of Internal Medicine·Kyung Jin KimYoung Moo Ro
Feb 19, 2021·Circulation Journal : Official Journal of the Japanese Circulation Society·Masakazu YamagishiUNKNOWN Japanese Circulation Society Working Group