Significant correlations of dermal total carotenoids and dermal lycopene with their respective plasma levels in healthy adults.

Archives of Biochemistry and Biophysics
Stephanie ScarmoSusan T Mayne

Abstract

Carotenoids in skin have been known to play a role in photoprotection against UV radiation. We performed dermal biopsies of healthy humans (N=27) and collected blood samples for pair-wise correlation analyses of total and individual carotenoid content by high performance liquid chromatography (HPLC). The hydrocarbon carotenoids (lycopene and beta-carotene) made up the majority of carotenoids in both skin and plasma, and skin was somewhat enriched in these carotenoids relative to plasma. Beta-cryptoxanthin, a monohydroxycarotenoid, was found in similar proportions in skin as in plasma. In contrast, the dihydroxycarotenoids, lutein and zeaxanthin, were relatively lacking in human skin in absolute and relative levels as compared to plasma. Total carotenoids were significantly correlated in skin and plasma (r=0.53, p<0.01). Our findings suggest that human skin is relatively enriched in lycopene and beta-carotene, compared to lutein and zeaxanthin, possibly reflecting a specific function of hydrocarbon carotenoids in human skin photoprotection.

References

Mar 1, 1996·Free Radical Research·H K BiesalskiH P Gollnick
Sep 20, 2002·Skin Pharmacology and Applied Skin Physiology·Anne-Katrin GreulHarald Gollnick
Feb 8, 2006·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Marisa Rodriguez-CarmonaJohn L Barbur
Jun 24, 2006·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Jessica KvansakulJohn L Barbur
May 1, 2009·Biochemistry·Prakash BhosalePaul S Bernstein
Aug 6, 2010·The American Journal of Clinical Nutrition·Susan T MayneWerner Gellermann

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Citations

Jul 5, 2013·Archives of Biochemistry and Biophysics·Susan T MayneWerner Gellermann
Jul 13, 2013·Archives of Biochemistry and Biophysics·Nancy E MoranSteven K Clinton
Jul 11, 2013·Investigative Ophthalmology & Visual Science·Bradley S HenriksenPaul S Bernstein
Jan 30, 2014·Nutrients·Joanna Fiedor, Květoslava Burda
Aug 22, 2015·International Journal of Food Sciences and Nutrition·Roberto MassentiRiccardo Lo Bianco
Mar 1, 2012·Journal of Cosmetic Dermatology·Talita Pizza Anunciato, Pedro Alves da Rocha Filho
Sep 29, 2011·Molecular Nutrition & Food Research·Wilhelm Stahl, Helmut Sies
May 31, 2015·Archives of Dermatological Research·Lethicia SokoloskiEdiléia Bagatin
Mar 8, 2013·Dermato-endocrinology·Silke K SchagenChristos C Zouboulis
Oct 6, 2005·Physiology & Behavior·Kevin J McGraw, Robert S Parker
Apr 17, 2012·Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición·Robinson Ramírez-VélezRicardo Antonio Agredo-Zúñiga
Mar 12, 2015·Anais Brasileiros De Dermatologia·Sérgio SchalkaUNKNOWN Brazilian Society of Dermatology
Oct 12, 2012·The American Journal of Clinical Nutrition·Wilhelm Stahl, Helmut Sies
Aug 3, 2019·Antioxidants·Anamaria Balić, Mislav Mokos
Nov 19, 2018·Journal of Dairy Science·Marina P ChernyshovaIvan M Petyaev
Jun 30, 2019·Scientific Reports·Akira ObanaPaul S Bernstein
Mar 20, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Pedapati S C Sri Harsha, Vera Lavelli
Nov 4, 2021·Journal of the Academy of Nutrition and Dietetics·Vivien W FamRobert M Hackman

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