Significant reduction of antibiotic consumption and patients' costs after an action plan in China, 2010-2014

PloS One
Lidao BaoHaijun Lyu

Abstract

On July 1, 2011, the Chinese government launched a national Action Plan for antibiotic stewardship targeting antibiotic misuse in public hospitals. The aim of this study was to evaluate the impacts of the Action Plan in terms of frequency and intensity of antibiotic utilization and patients costs in public general hospitals. Administrative pharmacy data from July 2010 to June 2014 were sampled from 65 public general hospitals and divided into three segments: (1) July 2010 to June 2011 as the preparation period; (2) July 2011 to June 2012 as the intervention period; and (3) July 2012 to June 2014 as the assessment period. The outcome measures included (1) antibiotic prescribing rates; (2) intensity of antibiotic consumption; (3) patients costs; and (4) duration of peri-operative antibiotic treatment in clean surgeries of thyroidectomy, breast, hernia, and orthopedic procedures. Longitudinal and cross-sectional analyses were conducted. Longitudinal analyses showed significant trend changes in the frequency and intensity of antibiotic consumption, the patients' costs on antibiotics, and the duration of antibiotic treatment received by surgical patients undergoing the 4 clean procedures during the intervention period. Cross-section...Continue Reading

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Citations

Feb 20, 2016·The Journal of Antimicrobial Chemotherapy·Hai LinCecilia Stålsby Lundborg
Jan 11, 2019·Antimicrobial Resistance and Infection Control·Di ZhangYalin Dong
Jun 23, 2019·BMJ : British Medical Journal·Ping HeQingyue Meng
Apr 27, 2018·Bulletin of the World Health Organization·Christophe Van DijckJanneke Arnoldine Cox
Jul 12, 2019·Transactions of the Royal Society of Tropical Medicine and Hygiene·Jia YinCecilia Stålsby Lundborg
Nov 12, 2015·Deutsches Ärzteblatt International·Karen ScholzeJan R Ortlepp
Jul 11, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Hui LiXiaoxv Yin
Oct 30, 2020·Clinical Epidemiology·Juan Carlos Bazo-AlvarezIrene Petersen
Apr 8, 2019·Médecine et maladies infectieuses·M L SilvaC Dumartin
Nov 21, 2021·International Journal of Clinical Pharmacy·Anna Leena LohinivaMaha Talaat

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Software Mentioned

SAS
Statistics Analysis System ( SAS

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