SILDENAFIL CITRATE INDUCED RETINAL TOXICITY-ELECTRORETINOGRAM, OPTICAL COHERENCE TOMOGRAPHY, AND ADAPTIVE OPTICS FINDINGS

Retinal Cases & Brief Reports
Fatoumata YanogaRichard B Rosen

Abstract

To report a case of persistent retinal toxicity associated with a high dose of sildenafil citrate intake. Single retrospective case report. A 31-year-old white man with no medical history presented with complaints of bilateral multicolored photopsias and erythropsia (red-tinted vision), shortly after taking sildenafil citrate-purchased through the internet. Patient was found to have cone photoreceptor damage, demonstrated using electroretinogram, optical coherence tomography, and adaptive optics imaging. The patient's symptoms and the photoreceptor structural changes persisted for several months. Sildenafil citrate is a widely used erectile dysfunction medication that is typically associated with transient visual symptoms in normal dosage. At high dosage, sildenafil citrate can lead to persistent retinal toxicity in certain individuals.

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Dec 30, 2016·JAMA Ophthalmology·Hoon Dong KimYoung-Hoon Ohn

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Citations

Dec 29, 2020·American Journal of Ophthalmology Case Reports·D Jackson ColemanStephen H Tsang
Apr 4, 2021·Biomedicines·Eva AusóGema Esquiva
Jun 28, 2021·Survey of Ophthalmology·Supriya AroraJay Chhablani
Jul 11, 2021·Ophthalmology Retina·Mark P BreazzanoStephen H Tsang

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