Silencing HIV-1 In Vivo

Cell
Frank Kirchhoff

Abstract

RNA interference holds great promise for antiviral therapy, but delivering effective quantities of small interfering RNAs (siRNAs) into the right target cells in vivo represents a major challenge. Kumar et al. (2008) now report a technique to target siRNAs specifically to T cells to suppress viral infection in a humanized mouse model of HIV/AIDS.

References

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Citations

Aug 15, 2012·Molekuliarnaia biologiia·K V GlebovaM Iu Skoblov
Jul 31, 2012·Future Virology·Shailendra K SaxenaMadhavan Pn Nair
Aug 1, 2010·Therapeutic Delivery·Bruno Sarmento
Aug 5, 2014·Biological & Pharmaceutical Bulletin·Yukinobu KodamaHitoshi Sasaki
Jan 22, 2010·Expert Opinion on Biological Therapy·Sandesh SubramanyaPremlata Shankar
May 1, 2012·Nanomedicine : Nanotechnology, Biology, and Medicine·Longzhu PiaoRobert J Lee
Oct 25, 2011·Journal of Controlled Release : Official Journal of the Controlled Release Society·Norihito YonenagaNaoto Oku
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Aug 14, 2012·Small·Sung Tae KimVincent M Rotello
Nov 17, 2010·The FEBS Journal·Min Suk Shim, Young Jik Kwon
Dec 15, 2016·Molecular Pharmacology·Keiichiro OkuhiraMikihiko Naito

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