Silent corticotroph adenoma with multiple cysts: Pars intermedia tumor?

Endocrine Pathology
Hiroshi NishiokaS L Asa

Abstract

A silent corticotroph adenoma with multiple cysts was found incidentally at autopsy. By immunohistochemistry, most of the adenoma cells contained reactivity for adrenocorticotropic hormone and beta-endorphin; a few cells stained for beta-subunit of luteinizing hormone. The cysts, interspersed within the tumor, were lined by cuboidal epithelium with foci of stratified squamous epithelium. The lining cells contained immunoreactive keratin; some cells were positive for S-100 protein or glial fibrillary acidic protein, and a few cells were also immuno-stained for adrenocorticotropic hormone and beta-endorphin. It is suggested that this tumor may represent a neoplasm of pars intermedia derivation.

References

Jan 1, 1987·Virchows Archiv. A, Pathological Anatomy and Histopathology·G Gon
Jan 1, 1989·Surgical Neurology·S NakasuH Okabe
Nov 1, 1989·Trends in Endocrinology and Metabolism : TEM·K KovacsT Sano

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Citations

Nov 15, 1997·Microscopy Research and Technique·A M McNicol

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