Silent ST-T changes in an epidemiologic cohort study--a marker of hypertension or coronary heart disease, or both: the Reykjavik study

Journal of the American College of Cardiology
E SigurdssonG Thorgeirsson

Abstract

We sought to evaluate the prognostic value and clinical characteristics associated with electrocardiographic (ECG) ST-T changes among men without other manifestations of coronary heart disease. Recent achievements in secondary prevention and treatment of coronary heart disease have highlighted the importance of early diagnosis of both symptomatic and silent forms of the disease. The prognostic and clinical importance of ST-T changes in men with no other manifestations of coronary heart disease is still unclear. Do they reflect silent coronary heart disease or hypertension, or both, and what is their independent contribution to prognosis? The subjects were 9,139 men born in the years 1907 to 1934 and followed up for 4 to 24 years. On initial visit they were assigned to different categories of coronary heart disease on the basis of Rose chest pain questionnaire, hospital records, 12-lead ECG, history and physical examination. The prevalence of silent ST-T changes among men without overt coronary heart disease was strongly influenced by age, increasing from 2% at age 40 years to 30% at age 80 years. Men with such ST-T changes were older and had higher serum triglyceride levels and worse glucose tolerance than men without such chan...Continue Reading

References

Jun 1, 1978·British Heart Journal·G RoseP McCartney
Mar 1, 1977·British Journal of Preventive & Social Medicine·G RoseD D Reid
Feb 1, 1976·The American Journal of Cardiology·W B Kannel
Oct 1, 1992·The New England Journal of Medicine·E D FrohlichB Massie
Feb 8, 1992·BMJ : British Medical Journal·E G SchoutenM L Simoons
Nov 1, 1989·Japanese Circulation Journal·M MurayamaK Sotozono
Jan 29, 1988·The American Journal of Cardiology·P F Cohn
Feb 1, 1987·American Heart Journal·B E KregerW B Kannel
Jan 1, 1968·Monograph Series·G A Rose, H Blackburn
Mar 1, 1970·The American Journal of Cardiology·L D Ostrander
Mar 1, 1982·British Heart Journal·K CullenG N Cumpston
Jun 1, 1982·British Heart Journal·S W RabkinR B Tate
Jun 1, 1984·British Heart Journal·A G ShaperP W Macfarlane
Feb 1, 1995·International Journal of Epidemiology·E SigurdssonG Thorgeirsson
May 1, 1993·European Heart Journal·E SigurdssonN Sigfusson

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Citations

Oct 29, 2008·Herzschrittmachertherapie & Elektrophysiologie·Bernd-Dieter Gonska
Sep 6, 2005·Cardiovascular Drugs and Therapy·Larus S GudmundssonJacqueline C M Witteman
Dec 14, 2005·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Andrea De LorenzoDaniel S Berman
Jul 20, 2001·Archives of Gerontology and Geriatrics·A YamamotoK Kangawa
Oct 24, 2002·Journal of the American College of Cardiology·Gilles F H DiercksWiek H van Gilst
Sep 19, 1998·Journal of the American College of Cardiology·D De BacquerH Blackburn
May 20, 1999·Journal of the American College of Cardiology·D De BacquerH Blackburn
Sep 8, 2006·Journal of Hypertension·Johannes BaulmannThomas Mengden
May 3, 2001·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·P M OkinB V Howard
Jul 6, 2014·Journal of Research in Pharmacy Practice·Farzad GheshlaghiNastaran Eizadi-Mood
Apr 25, 2000·Journal of Hypertension·J JanasR M Janas
Mar 8, 2000·Current Problems in Cardiology·E A AshleyV F Froelicher
Oct 3, 2006·Journal of the American College of Cardiology·Michael H Lehmann
Aug 12, 1999·Journal of the American Geriatrics Society·L I KatzelA P Goldberg
Jun 7, 2005·Journal of the American College of Cardiology·Peter M OkinRichard B Devereux
Jun 12, 2004·Current Problems in Cardiology·Gregory EngelPaul J Wang
Sep 5, 2001·Progress in Cardiovascular Diseases·E A AshleyV Froelicher
May 13, 2014·Journal of the American Heart Association·Peter Vibe RasmussenAnders Gaarsdal Holst
Mar 24, 2005·European Heart Journal·Gestur ThorgeirssonJacqueline Witteman

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