PMID: 8608686Nov 1, 1995Paper

Silicone breast implant--associated musculoskeletal manifestations

Clinical Rheumatology
M L CuellarR Espinoza

Abstract

Three hundred consecutive women with silicone breast implants (SBI), referred to the arthritis clinic with a variety of musculoskeletal complaints, were evaluated for the presence of underlying connective tissue disease. A complete history and physical examination were performed, as well as laboratory testing for C-reactive protein, rheumatoid factor; and autoantibody determination by indirect immunofluorescence and immunodiffusion. The group mean age was 44.4 years (range 25-69), the mean time from initial implant surgery to appearance of symptoms was 6.8 years (range: 6m-19y) and 83.3% of women studied had clinical manifestations highly suggestive of an underlying connective tissue disorder. Fifty-four percent met criteria for fibromyalgia and/or chronic fatigue syndrome, distinct connective tissue diseases was detected in 11%, undifferentiated connective tissue disease or human adjuvant disease was found in 10.6%, and a variety of disorders such as angioneurotic oedema, frozen shoulder, multiple sclerosis-like syndrome were present. Several other miscellaneous conditions including recurrent unexplained low grade fever, hair loss, skin rash, sicca symptoms, Raynaud's phenomenon, carpal tunnel syndrome, memory loss, headaches,...Continue Reading

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Citations

Oct 1, 1996·Arthritis and Rheumatism·N R Rose
Jan 1, 1996·Clinical Rheumatology·G Bernard-MedinaJ Orozco-Alcala
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May 1, 2021·International Journal of Environmental Research and Public Health·Todor I TodorovPrabath W B Nanayakkara

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