PMID: 9433399Jan 1, 1997Paper

Silicone breast implants and systemic rheumatic disease. Some smoke but little fire to date

Scandinavian Journal of Rheumatology
M H Liang

Abstract

For over 20 years silicone breast implants have been used for cosmetic and breast reconstruction purposes. They have been recently banned by the American Food and Drug Administration other than for reconstruction or in the setting of a study. Complications of rupture, leaking, bleeding, capsular thickening and contracture are acknowledged but the potential of silicone implants in causing classic rheumatic diseases or a new syndrome has caused much controversy; there are millions of dollars at stake in legal suits. The biological plausibility of silicone breast implants causing disease is not without merit. The epidemiological evidence linking the two are reviewed. There is considerable concern as to whether there will ever be a definitive study of the question.

References

Oct 1, 1994·Journal of Clinical Epidemiology·B L StromR Schinnar
Jun 22, 1995·The New England Journal of Medicine·J Sánchez-GuerreroM H Liang
Feb 1, 1994·Arthritis and Rheumatism·J Sánchez-GuerreroM H Liang
Jun 16, 1994·The New England Journal of Medicine·S E GabrielL J Melton
Feb 28, 1996·JAMA : the Journal of the American Medical Association·C H HennekensJ E Buring
Jul 1, 1996·Arthritis and Rheumatism·M C HochbergF M Wigley
Oct 1, 1996·Arthritis and Rheumatism·D M Marcus

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Citations

Feb 28, 2002·Contraception·Prasad Venkatram Shastri
Jan 23, 1999·Current Opinion in Rheumatology·R M Bernstein
Jun 29, 2000·Neurologic Clinics·J W Albers, S Berent
Feb 5, 2003·Clinical Orthopaedics and Related Research·Charles A Engh

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