Silicone gel-filled breast implants in women: findings at H-1 MR spectroscopy

Radiology
B PfleidererL Garrido

Abstract

To evaluate, at hydrogen-1 magnetic resonance (MR) spectroscopy, the effect of implantation time, implant status, and implant removal on the amount of silicone in the liver in women with silicone gel-filled breast prostheses. The study population included 55 women (39 patients with silicone gel-filled prostheses and seven from whom implants had been removed, and nine control subjects [eight with no implant and one with saline-filled implants]). Stimulated-echo acquisition mode, or STEAM, H-1 MR spectroscopy was performed to determine the concentration of silicone in the liver. Implant status at the time of spectroscopy was diagnosed at MR imaging. Twenty of 39 (51%) women with implants had ruptured prostheses. Resonances associated with the presence of silicone and partially hydrolyzed silicone (0.3 to -0.8 ppm with respect to water at 4.7 ppm) and other resonances that are not yet assigned (-2 to -5 ppm) were detected in 27 (69%) of the 39 women (17 with ruptured implants). Relative signal intensities of the silicone species detected in the liver in these women were found to vary substantially and were not correlated with the status of the implants (P > .70). Silicone resonances were not detected in the livers in the nine cont...Continue Reading

Citations

Jan 24, 2002·AJR. American Journal of Roentgenology·Wendie A BergS Lori Brown
Jun 1, 2002·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Imke BernerBettina Pfleiderer
Jul 11, 1998·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R HaselhorstJ Seelig
Aug 3, 2010·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Simon BrunnerSusanne Binder
Feb 18, 2003·Analytical and Bioanalytical Chemistry·Daniela FlassbeckAlfred V Hirner
Feb 20, 2019·AJR. American Journal of Roentgenology·Katrina N GlazebrookJoel G Fletcher
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