Silicone implant to prevent visceral damage during adjuvant radiotherapy for retroperitoneal sarcoma

The British Journal of Radiology
A B BallJ M Thomas


The incidence of local recurrence after surgery for retroperitoneal sarcoma is reduced by high-dose adjuvant radiotherapy but treatment is restricted by the effects of irradiation on adjacent viscera. By securing a silicone gel-filled implant (breast prosthesis) in the tumour bed after excision of the tumour, adjacent viscera are displaced from the site of maximum irradiation and may thereby be protected. We used this technique in three patients in whom excision of a retroperitoneal sarcoma was followed by high-dose adjuvant radiotherapy. Post-operative radiotherapy was well tolerated but local recurrence developed in one patient, and delayed perforation of the large bowel occurred in another. Both cases underwent further surgery at which the implant was removed. The same two cases also developed asymptomatic hydronephrosis on the side of the implant, attributed to local fibrosis.


Jan 1, 1988·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·T J KinsellaS A Rosenberg
Aug 1, 1987·The British Journal of Surgery·R B Galland, J Spencer
Sep 1, 1986·Journal of the Medical Association of Georgia·J Duttenhaver
Aug 1, 1984·Annals of Surgery·P C McGrathG A Parker
Jun 1, 1984·International Journal of Radiation Oncology, Biology, Physics·J E TepperP McNulty
Feb 1, 1982·International Journal of Radiation Oncology, Biology, Physics·N Einhorn
May 1, 1981·Cancer·H S CodyS I Hajdu
Jan 1, 1981·Journal of Surgical Oncology·F K StormD L Morton

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