Silicone implants and lymphoma: The role of inflammation

Journal of Autoimmunity
Mojca BizjakYehuda Shoenfeld

Abstract

The risk of hematological malignancies is mainly determined by genetic background, age, sex, race and ethnicity, geographic location, exposure to certain chemicals and radiation; along with the more recently proposed immune factors such as chronic inflammation, immunodeficiencies, autoimmunity, and infections. Paradigmatic examples include the development of lymphoma in Sjögren's syndrome and Hashimoto thyroiditis, gastric MALT lymphoma in Helicobacter pylori infection, or lymphomas associated with infections by Epstein-Barr virus, human herpes virus 8 (HHV 8) and leukemia/lymphoma virus 1 (HTLV-1). A growing number of reports indicates an increased risk of lymphoma, particularly of the anaplastic large cell (ALCL) type. The implants, specifically those used in the past, elicit chronic stimulation of the immune system against the prosthetic material. This is particularly the case in genetically susceptible hosts. We suggest that polyclonal activation may result in monoclonality in those at risk hosts, ultimately leading to lymphoma. We suggest that patients with an inflammatory response against silicone implants be monitored carefully.

References

Apr 4, 1977·JAMA : the Journal of the American Medical Association·A J ChristieM Dietrich
Oct 20, 1975·JAMA : the Journal of the American Medical Association·R Ellenbogen, L Rubin
Sep 1, 1986·The Journal of Hand Surgery·C A PeimerC S Howard
Jan 1, 1982·Aesthetic Plastic Surgery·B Milojevic
Apr 1, 1996·Plastic and Reconstructive Surgery·L T YuN S Hardt
Jan 1, 1995·Advances in Experimental Medicine and Biology·J O Naim, C J van Oss
Aug 1, 1997·Plastic and Reconstructive Surgery·J A Keech, B J Creech
Jan 4, 1998·Journal of Biomedical Materials Research·J O NaimC J van Oss
Nov 3, 1998·Journal of Clinical Pathology·P J van DiestJ J Hage
Jul 27, 1999·Annals of the Rheumatic Diseases·C J SchaeferP H Wooley
May 9, 2000·Clinical and Diagnostic Laboratory Immunology·J O NaimW H Reeves
Oct 13, 2001·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·S B KeelA E Rosenberg
Mar 23, 2002·Leukemia & Lymphoma·Guylaine GaudetArnold S Freedman
Feb 14, 2003·Respiration; International Review of Thoracic Diseases·Cheol Hyeon KimYoung Whan Kim
Jan 18, 2005·Autoimmunity Reviews·Manuel Ramos-CasalsAthanasios G Tzioufas
Mar 1, 2005·The Annals of Thoracic Surgery·Nicolas M DürrlemanBernard Albat
Sep 20, 2006·Virchows Archiv : an International Journal of Pathology·Florian Rudolf FritzscheGlen Kristiansen
May 19, 2007·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Michael K NewmanBrian J Kaplan
May 31, 2007·Annals of the Royal College of Surgeons of England·D BodiwalaT R Terry
Jan 29, 2008·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Anja C RodenAhmet Dogan
Apr 4, 2008·Cancer Causes & Control : CCC·Arti Parikh-PatelRosemary Cress
May 30, 2008·Pacing and Clinical Electrophysiology : PACE·Jan NemecAla A Shalaby
Jul 3, 2008·The American Journal of Surgical Pathology·Anna K WongShikha Bose
Jul 9, 2008·World Journal of Urology·M C G BleekerC J L M Meijer
Nov 6, 2008·JAMA : the Journal of the American Medical Association·Daphne de JongFlora E van Leeuwen
Mar 26, 2009·JAMA : the Journal of the American Medical Association·Astrid A M van der VeldtPrabath W Nanayakkara
Apr 9, 2009·Interactive Cardiovascular and Thoracic Surgery·Izhar N BagwanMary N Sheppard
May 15, 2009·Clinical and Experimental Dermatology·L SagiE Winkler
Jun 24, 2009·Annals of Plastic Surgery·Tamir GilYaron Har-Shai
Jun 30, 2009·Leukemia & Lymphoma·Daniela MoruzzoMaido Castiglioni
Jul 25, 2009·The Breast Journal·Adrian DraguGiulio Ingianni
Aug 29, 2009·European Journal of Internal Medicine·Nicolas KlugerLoïc Guillevin
Nov 3, 2009·Lupus·E IsraeliY Shoenfeld
Dec 31, 2009·Interactive Cardiovascular and Thoracic Surgery·Sridhar RathinamManinder S Kalkat
Jan 22, 2010·Rheumatology·Catherine L HillPeter Roberts-Thomson
Feb 9, 2010·The American Journal of Surgical Pathology·Dylan V MillerAndrew L Feldman
Jul 3, 2010·Plastic and Reconstructive Surgery·Summer E Hanson, Karol A Gutowski
Sep 28, 2010·The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons·Bharath PalrajLarry M Bush
Mar 2, 2011·Plastic and Reconstructive Surgery·Benjamin KimSoeren Mattke
May 10, 2011·Aesthetic Surgery Journal·Felmont Eaves, Foad Nahai
Jun 28, 2011·Leukemia & Lymphoma·Leslie PopplewellStephen J Forman

❮ Previous
Next ❯

Citations

Jul 16, 2016·Immunologic Research·Jiram Torres RuizYehuda Shoenfeld
Oct 16, 2016·International Journal of Clinical Oncology·Helen Ma, Maher Abdul-Hay
Apr 20, 2017·International Journal of Surgical Pathology·Andres Mosquera-ZamudioSamuel D Morales
Jul 15, 2016·Immunologic Research·M de BoerJ W Cohen Tervaert
Feb 6, 2017·Plastic and Reconstructive Surgery·Erin L DorenMark W Clemens
Apr 6, 2017·Current Opinion in Rheumatology·Jan Willem Cohen TervaertRené R van der Hulst
Apr 4, 2017·Current Opinion in Rheumatology·Laura Andreoli, Angela Tincani
Sep 16, 2017·Plastic and Reconstructive Surgery·Campanale AntonellaMarletta Marcella
Mar 30, 2018·Plastic and Reconstructive Surgery·Mark W ClemensRoberto N Miranda
Apr 5, 2018·Cancers·Ivonne A Montes-MojarroFalko Fend
Dec 19, 2017·Case Reports in Plastic Surgery & Hand Surgery·Alexandre Mendonça MunhozRoberto De Mezerville
Jun 8, 2018·Plastic and Reconstructive Surgery·Aaron C Van SlykeNicholas J Carr
Mar 1, 2019·Plastic and Reconstructive Surgery·Gregory A LamarisMark W Clemens
Jun 11, 2019·Plastic and Reconstructive Surgery·José MendesFlavia F S Zacchi
Jul 28, 2020·Archives of Plastic Surgery·Peera ThienpaitoonNaree Warnnissorn
Dec 28, 2017·Plastic and Reconstructive Surgery·Antonella CampanaleMarcella Marletta
Dec 28, 2017·Plastic and Reconstructive Surgery·Maurizio Bruno NavaNicola Rocco
Aug 11, 2018·Current Opinion in Oncology·Camille LaurentPhilippe Gaulard
Aug 29, 2019·Plastic and Reconstructive Surgery·José MendesFlavia F S Zacchi
Apr 11, 2018·Cytopathology : Official Journal of the British Society for Clinical Cytology·A RonchiI Cozzolino
Nov 18, 2018·Inflammation·Monia OrcianiRoberto Di Primio
Sep 13, 2018·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Arianna Di NapoliGovind Bhagat
Jan 28, 2019·Virchows Archiv : an International Journal of Pathology·Thomas MenterStefan Dirnhofer
Jun 8, 2019·Journal of Medical Imaging and Radiation Oncology·Ruvini Thashila GunawardanaDonna B Taylor
Mar 11, 2020·Aesthetic Plastic Surgery·Maria-Isabel Caravantes-CortesAdrian-Alejandro Carballo-Zarate
Dec 12, 2017·Case Reports in Oncological Medicine·Daniel E EzekwudoIshmael Jaiyesimi
Oct 31, 2018·Deutsches Ärzteblatt International·Julian KricheldorffUwe von Fritschen
Dec 17, 2020·Journal of Clinical Medicine·Giuseppe IngravalloSaverio Capodiferro
Oct 16, 2020·Biomolecules·Vânia BorbaYehuda Shoenfeld
Jan 31, 2021·International Journal of Molecular Sciences·Elisabeth DigificoCristina Belgiovine
Apr 3, 2021·Journal of Autoimmunity·Gilad HalpertYehuda Shoenfeld
Apr 24, 2021·Plastic and Reconstructive Surgery·M Bradley Calobrace

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Related Papers

Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
T Chiba
Gastroentérologie Clinique Et Biologique
P MoussuJ L Balmes
AJR. American Journal of Roentgenology
M S LevineM I Goldwein
© 2021 Meta ULC. All rights reserved