Silk: molecular organization and control of assembly

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
Regina ValluzziD L Kaplan

Abstract

The interface between the science and engineering of biology and materials is an area of growing interest. One of the goals of this field is to utilize biological synthesis and processing of polymers as a route to gain insight into topics such as molecular recognition, self-assembly and the formation of materials with well-defined architectures. The biological processes involved in polymer synthesis and assembly can offer important information on fundamental interactions involved in the formation of complex material architectures, as well as practical knowledge into new and important materials related to biomaterial uses and tissue engineering needs. Classic approaches in biology, including genetic engineering, controlled microbial physiology and enzymatic synthesis, are prototypical methods used to control polymer structure and chemistry, including stereoselectivity and regioselectivity, to degrees unattainable using traditional synthetic chemistry. This type of control can lead to detailed and systematic studies of the formation of the structural hierarchy in materials and the subsequent biological responses to these materials.

References

May 26, 1999·International Journal of Biological Macromolecules·R ValluzziD Kaplan
Apr 25, 2000·Biophysical Journal·D WilsonD Kaplan
Jan 5, 2002·Journal of Biotechnology·S Winkler, D L Kaplan

❮ Previous
Next ❯

Citations

Jun 14, 2005·Current Opinion in Biotechnology·Thomas Scheibel
May 24, 2007·Tissue Engineering·Lorenz UebersaxLorenz Meinel
Apr 18, 2014·International Journal of Nanomedicine·Pu ShiJ Andrew MacKay
Nov 26, 2015·Acta Biomaterialia·Sonia Kapoor, Subhas C Kundu
Apr 24, 2012·Advanced Drug Delivery Reviews·Lorenz Meinel, David L Kaplan
Jul 23, 2015·Stem Cells International·Weimin GuoQuanyi Guo
Nov 6, 2009·Macromolecular Bioscience·Olena S RabotyagovaDavid L Kaplan
Nov 19, 2015·Journal of Controlled Release : Official Journal of the Controlled Release Society·Jordan DespanieJ Andrew MacKay
Feb 7, 2006·Journal of Controlled Release : Official Journal of the Controlled Release Society·S HofmannL Meinel
Jun 16, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Brett WalletVladimir V Tsukruk
Jun 27, 2018·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Megan K DeBari, Rosalyn D Abbott
Apr 3, 2008·Journal of Tissue Engineering and Regenerative Medicine·Ana C MacIntoshPaul V Hatton
Apr 17, 2008·Angewandte Chemie·Izhack Cherny, Ehud Gazit
Jan 6, 2009·The Journal of Eukaryotic Microbiology·Jitender P Dubey
Feb 18, 2010·Journal of Materials Chemistry·Amanda R Murphy, David L Kaplan
May 4, 2012·Advanced Materials·Hu TaoFiorenzo G Omenetto
Jun 9, 2017·Annual Review of Chemical and Biomolecular Engineering·Yun Jung YangBradley D Olsen
Nov 22, 2019·MRS Communications·Anton Kan, Neel S Joshi
Jan 22, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Wonkyung AhnEun Jung Lee
Feb 18, 2021·Biomedical Materials·Maryam FarokhiHeinz Redl
May 9, 2016·ACS Biomaterials Science & Engineering·Emanuela CalloneAntonella Motta
Aug 25, 2021·Biomedical Materials·Deboki NaskarSubhas C Kundu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.