Silver nanoparticle deposited implants to treat osteomyelitis

Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Samit Kumar NandiAmit Bandyopadhyay

Abstract

In this study, electrolytically deposited strongly adherent silver nanoparticles on stainless-steel (SS) implants were used for in situ osteomyelitis treatment. Samples were heat treated to enhance adhesion of silver on 316 L SS. Ex vivo studies were performed to measure silver-release profiles from the 316 L SS screws inserted in equine cadaver bones. No change in the release profiles of silver ions were observed in vitro between the implanted screws and the control. In vivo studies were performed using osteomyelitic rabbit model with 3 mm diameter silver-deposited 316 L SS pins at two different doses of silver: high and low. Infection control ability of the pins for treating osteomyelitis in a rabbit model was measured using bacteriologic, radiographic, histological, and scanning electron microscopic studies. Silver-coated pins, especially high dose, offered a promising result to treat infection in animal osteomyelitis model without any toxicity to major organs. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 1073-1083, 2018.

References

Jun 1, 1990·Journal of Biomedical Materials Research·T KokuboT Yamamuro
Jan 1, 1987·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·P J RespetB P Meinhard
Jun 1, 1974·Canadian Journal of Microbiology·P D Bragg, D J Rainnie
Oct 1, 1973·Biochemical Pharmacology·S M Modak, C L Fox
May 1, 1996·Critical Reviews in Toxicology·M A Hollinger
Nov 1, 1996·The American Journal of Medicine·D W Haas, M P McAndrew
Apr 3, 1997·The New England Journal of Medicine·D P Lew, F A Waldvogel
Dec 30, 1998·The Journal of Hospital Infection·J M SchierholzG Pulverer
Apr 2, 1999·Clinical Orthopaedics and Related Research·K Tetsworth, G Cierny
Jun 24, 1999·Infection·J GreilJ P Guggenbichler
Mar 21, 2000·International Journal of Antimicrobial Agents·G CookR O Darouiche
Jun 28, 2003·The American Journal of Medicine·Alan D TiceDavid A Shoultz
Feb 1, 1963·Health Physics·I H TIPTON, M J COOK
Oct 7, 2004·The Journal of Bone and Joint Surgery. American Volume·Luca LazzariniJason H Calhoun
Dec 4, 2004·Biomaterials·Radhesh Kumar, Helmut Münstedt
Dec 4, 2004·Clinical Orthopaedics and Related Research·Javad ParviziNoreen J Hickok
Jan 18, 2005·Journal of Controlled Release : Official Journal of the Controlled Release Society·Pavan Kumar NaraharisettiChi-Hwa Wang
Jun 7, 2005·The Journal of Hospital Infection·K Davenport, F X Keeley
Mar 8, 2008·Journal of Controlled Release : Official Journal of the Controlled Release Society·Qingguo Xu, Jan T Czernuszka
Apr 16, 2008·Antimicrobial Agents and Chemotherapy·Kyriaki KanellakopoulouHelen Giamarellou
May 17, 2008·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Kakoli DasBruce L Gibbins
Feb 24, 2010·Injury·Konstantinos N MalizosDionysios Paridis
Apr 2, 2010·ACS Applied Materials & Interfaces·D Matthew EbyGlenn R Johnson
Feb 2, 2011·The Journal of Bone and Joint Surgery. British Volume·M El-HusseinyF S Haddad
Jun 22, 2011·Journal of Materials Science. Materials in Medicine·M PolliniA Sannino
Jun 20, 2012·Materials Science & Engineering. C, Materials for Biological Applications·Paul DevasconcellosLewis G Zirkle
Apr 30, 2015·The Bone & Joint Journal·S A BrennanA Walsh
Mar 28, 2016·Journal of the Mechanical Behavior of Biomedical Materials·Anish ShivaramAmit Bandyopadhyay
Apr 10, 2016·BMC Musculoskeletal Disorders·Norbert HarrasserRainer Burgkart

❮ Previous
Next ❯

Citations

Mar 16, 2019·Journal of Medical Microbiology·Marta BottagisioArianna B Lovati
Dec 19, 2019·Journal of Materials Chemistry. B, Materials for Biology and Medicine·I A J van HengelA A Zadpoor
Apr 15, 2020·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Leah H CobbLauren B Priddy
Jun 21, 2019·Royal Society Open Science·Peng ZhangFeng Zhang
Nov 18, 2018·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Michael C WyattMichael R Whitehouse
Sep 5, 2018·Journal of Orthopaedic Surgery and Research·Chenhao PanXiaowei Yu
Aug 11, 2020·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Niyou WangA Senthil Kumar
Oct 3, 2020·Advances in Colloid and Interface Science·Marcel F KunrathMaría E Galárraga-Vinueza
Jul 7, 2021·Materials Science & Engineering. C, Materials for Biological Applications·Huan ZhouLei Yang

❮ Previous
Next ❯

Related Concepts

Related Feeds

CRISPR & Staphylococcus

CRISPR-Cas system enables the editing of genes to create or correct mutations. Staphylococci are associated with life-threatening infections in hospitals, as well as the community. Here is the latest research on how CRISPR-Cas system can be used for treatment of Staphylococcal infections.

Related Papers

Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Sheetal D'MelloAliasger K Salem
Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Marat O GallyamovAlexei R Khokhlov
Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Abdul Wahab JatoiIck Soo Kim
Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Nhayoung HongGeunHyung Kim
© 2022 Meta ULC. All rights reserved