Silver oxynitrate - an efficacious compound for the prevention and eradication of dual-species biofilms

Biofouling
Joe A LemireRaymond J Turner

Abstract

Preventing and eradicating biofilms remains a challenge in clinical and industrial settings. Recently, the present authors demonstrated that silver oxynitrate (Ag7NO11) prevented and eradicated single-species planktonic and biofilm populations of numerous microbes at lower concentrations than other silver (Ag) compounds. Here, the antimicrobial and anti-biofilm efficacy of Ag7NO11is elaborated by testing its in vitro activity against combinations of dual-species, planktonic and biofilm populations of Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. As further evidence emerges that multispecies bacterial communities are more common in the environment than their single-species counterparts, this study reinforces the diverse applicability of the minimal biofilm eradication concentration (MBEC™) assay for testing antimicrobial compounds against biofilms. Furthermore, this study demonstrated that Ag7NO11had enhanced antimicrobial and anti-biofilm activity compared to copper sulfate (CuSO4) and silver nitrate (AgNO3) against the tested bacterial species.

References

Aug 26, 1998·International Journal of Food Microbiology·C G Kumar, S K Anand
May 21, 1999·Science·J W CostertonE P Greenberg
Jul 21, 2001·Lancet·P S Stewart, J W Costerton
Apr 18, 2002·American Journal of Physiology. Heart and Circulatory Physiology·Chandan K SenSashwati Roy
Jun 9, 2006·Journal of Industrial Microbiology & Biotechnology·Simon SilverGregg Silver
Jun 13, 2006·Current Problems in Dermatology·Alan B G Lansdown
Oct 18, 2007·Nature Reviews. Microbiology·Joe J HarrisonRaymond J Turner
Mar 11, 2010·Journal of Wound Care·R D WolcottS E Dowd
Apr 10, 2010·The Journal of Antimicrobial Chemotherapy·Katja E HillDavid W Thomas
Apr 14, 2010·Expert Opinion on Pharmacotherapy·Howard CeriRaymond J Turner
Sep 22, 2010·Antimicrobial Agents and Chemotherapy·Victoria KostenkoRobert John Martinuzzi
Jan 5, 2011·Applied and Environmental Microbiology·Gregor GrassMarc Solioz
Apr 13, 2011·International Journal of Oral Science·Niels HøibyThomas Bjarnsholt
Nov 10, 2011·FEMS Immunology and Medical Microbiology·Liang YangMichael Givskov
Feb 28, 2013·Annals of Clinical Microbiology and Antimicrobials·May Lei MeiLakshman Perera Samaranayake
May 15, 2013·Nature Reviews. Microbiology·Joseph A LemireRaymond J Turner
Jun 19, 2013·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·Kristel MijnendonckxRob Van Houdt
Jun 21, 2013·Science Translational Medicine·Jose Ruben Morones-RamirezJames J Collins
Jul 6, 2013·Trends in Microbiology·Thomas BjarnsholtNiels Høiby
Aug 2, 2013·Annals of Plastic Surgery·Edward W MalinLeopoldo C Cancio
Aug 24, 2013·Biofouling·Alexandra MeierDouglas P Connelly
Sep 17, 2013·PloS One·Sarah L Warnes, C William Keevil
Feb 14, 2014·Advanced Healthcare Materials·Maggie HerronNicholas L Abbott
Sep 10, 2014·International Wound Journal·Daniel G Metcalf, Philip G Bowler
Apr 29, 2015·Antimicrobial Agents and Chemotherapy·Joe A LemireRaymond J Turner
Mar 24, 2016·Trends in Microbiology·Henriette L RøderMette Burmølle

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Citations

Jul 14, 2018·Annals of the New York Academy of Sciences·Lindsay R Kalan, Meghan B Brennan
Mar 13, 2018·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Helen A ThomasonMatthew J Hardman
Apr 28, 2018·Animal Frontiers : the Review Magazine of Animal Agriculture·Benjamin P WillingBenjamin C T Bourrie
Jul 10, 2018·Advances in Wound Care·Lindsay Kalan, Elizabeth A Grice
Dec 28, 2017·ACS Infectious Diseases·Heidi WolfmeierRobert E W Hancock
Feb 9, 2019·Journal of Medicinal Chemistry·Serenella MediciMaria Antonietta Zoroddu

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