Similar serovar and drug susceptibility profiles among AIDS-related Mycobacterium avium isolates from diverse geographic locations

The American Journal of the Medical Sciences
N J JacobsD J Dawson

Abstract

Serotyping was performed on Mycobacterium avium isolates from 40 AIDS patients from 5 geographic sites: Boston (17 patients), New Hampshire (4 patients), Finland (12 patients), Trinidad (3 patients), and Kenya (4 patients). Serovars were similar from the five sites. Serovars 4 and 8 were the most common. In addition, minimal inhibitory concentrations to 8 antimicrobial agents were determined for 31 of these isolates and for 21 additional patient isolates from these sites. Minimal inhibitory concentration90 values for clarithromycin, azithromycin, clofazimine, amikacin, ethambutol, ciprofloxacin, sparfloxacin, and rifabutin were similar for isolates from the five geographic sites. Antimicrobial susceptibility patterns did not differ by serovar.

References

Feb 1, 1995·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·C F GilksC F von Reyn

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