Similarities between static and rotational intensity-modulated plans

Physics in Medicine and Biology
Q Jackie WuShiva K Das

Abstract

The aim of this study was to explore similarities between intensity-modulated radiotherapy (IMRT) and intensity-modulated arc therapy (IMAT) techniques in the context of the number of multi-leaf collimator (MLC) segments required to achieve plan objectives, the major factor influencing plan quality. Three clinical cases with increasing complexity were studied: (a) prostate only, (b) prostate and seminal vesicles and (c) prostate and pelvic lymph nodes. Initial 'gold-standard' plans with the maximum possible organ-at-risk sparing were generated for all three cases. For each case, multiple IMRT and IMAT plans were generated with varying intensity levels (IMRT) and arc control points (IMAT), which translate into varying MLC segments in both modalities. The IMAT/IMRT plans were forced to mimic the organ-at-risk sparing and target coverage in the gold-standard plans, thereby only allowing the target dose inhomogeneity to be variable. A higher target dose inhomogeneity (quantified as D5--dose to the highest 5% of target volume) implies that the plan is less capable of modulation. For each case, given a similar number of MLC segments, both IMRT and IMAT plans exhibit similar target dose inhomogeneity, indicating that there is no diffe...Continue Reading

References

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Citations

Jan 11, 2012·Health Care Management Science·Delal DinkBehlul Saka
Jul 4, 2012·Radiological Physics and Technology·Motohiro KawashimaKeisuke Sasai
Jul 23, 2011·Medical Physics·Ivaylo B MihaylovMichael Kaus
Nov 18, 2011·Journal of Applied Clinical Medical Physics·Ivaylo B MihaylovEdward Sternick
Jun 24, 2010·Physics in Medicine and Biology·Xiaofeng ZhuQ Jackie Wu
Sep 21, 2013·Physics in Medicine and Biology·H H ZhangW D D'Souza

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