PMID: 6165394Mar 27, 1981Paper

Similarities between stratum corneum basic protein and histidine-rich protein II from newborn rat epidermis

Biochimica Et Biophysica Acta
B A DaleI A Bernstein

Abstract

The stratum corneum basic protein and histidine-rich protein II were each isolated from newborn rat epidermis and compared by biochemical and immunologic methods. The proteins were indistinguishable by immunodiffusion using antiserum elicited to either protein. The migration of the proteins on SDS-polyacrylamide gel electrophoresis was identical giving a molecular weight of 49 000. These proteins, which have similar but unusual amino acid compositions, give very similar tryptic peptide maps. Both proteins aggregate with keratin filaments to form macrofibrils. These results suggest that histidine-rich protein II and stratum corneum basic protein are the same protein. We suggest that this protein be called histidine-rich basic protein.

References

Feb 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·S H YenM L Shelanski
May 1, 1979·The Journal of Investigative Dermatology·B A Dale, S Y Ling
Aug 28, 1979·Biochimica Et Biophysica Acta·T MurozukaW L Epstein
Feb 1, 1979·Analytical Biochemistry·L E HendersonW Konigsberg
Jan 1, 1977·Methods in Enzymology·J R Benson
Jan 1, 1977·Methods in Enzymology·P E Hare
Dec 15, 1976·Journal of Molecular Biology·P M SteinertS B Zimmerman
Jan 1, 1976·Analytical Biochemistry·J H Waite, C Y Wang
Feb 1, 1972·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·S B Guss, A R Ugel
Dec 1, 1967·The Journal of Investigative Dermatology·K Fukuyama, W L Epstein
Aug 1, 1966·Proceedings of the National Academy of Sciences of the United States of America·J K Hoober, I A Bernstein
Nov 1, 1974·The Journal of Investigative Dermatology·T Tezuka, I M Freedberg
Dec 1, 1967·The Journal of Investigative Dermatology·J GumucioI A Bernstein
Feb 1, 1972·The Journal of Cell Biology·A R Ugel, W Idler
Dec 1, 1966·The Journal of Investigative Dermatology·K Fukuyama, W L Epstein

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Citations

Jan 1, 1991·Journal of Neural Transmission. Parkinson's Disease and Dementia Section·M R IssidoridesM D Yahr
Apr 1, 1984·Developmental Biology·C FisherE J Kollar
Jul 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·P M SteinertB A Dale
Mar 1, 1984·The Journal of Cell Biology·M E GilmartinI M Freedberg
Jan 1, 1982·Archives of Oral Biology·B A DaleA M Lynley
Jan 1, 1985·Annals of the New York Academy of Sciences·A VidrichI M Freedberg
Nov 15, 1985·Biochemical and Biophysical Research Communications·G M BhatnagarY M Bhatnagar
Jul 1, 1983·The Journal of Investigative Dermatology·B A DaleS H Yuspa

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