Simple model of double adiabatic inversion (DAI) efficiency

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
H Michael Gach, Weiying Dai

Abstract

Multislice continuous arterial spin labeling (CASL) using alternating single adiabatic inversion (SAI) and double adiabatic inversion (DAI) (ASD) suffers from control inefficiencies that reduce the perfusion signal-to-noise ratio (SNR). A simple analytic model for DAI efficiency (chi) is presented, and compared with simulation and experimental data. The DAI efficiency (defined as the ratio of uninverted to equilibrium spins) depends primarily on the effective adiabaticity (beta') and the inversion time (both determined from the labeling RF field and gradient amplitudes, and flow velocities). In this study, chi behaved like a damped oscillator, starting from 1 at beta'=0 (no spin inversion), dropping to 0.5 at beta'=0.5 (spin saturation), rising again to a peak at beta' approximately 3, and subsequently oscillating at higher beta'. The simple model matched the flow phantom data for beta' < 2, with an accuracy of better than 10%, but it diverged from the flow phantom data as the data oscillated at higher beta'. The relative inversion efficiencies of ASD and simultaneous proximal and distal irradiation (SPDI) were measured in 28 elderly volunteers. The ratio of CASL difference (control-label) signals measured in gray matter (= 1.1...Continue Reading

References

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Jan 24, 2003·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jane F UttingRoger J Ordidge

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Citations

Jan 5, 2008·Stroke; a Journal of Cerebral Circulation·Weiying DaiH Michael Gach
Jul 25, 2006·The British Journal of Radiology·E T PetersenX Golay
Mar 31, 2005·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Theodore R StegerEdward F Jackson
Nov 26, 2008·Journal of Magnetic Resonance Imaging : JMRI·Weiying DaiH Michael Gach
Nov 26, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Weiying DaiDavid C Alsop
May 5, 2006·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Ruth L O'GormanDavid J Lythgoe
Apr 22, 2005·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Richard WernerOlav Jansen
Aug 9, 2005·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jane F UttingRoger J Ordidge
Jul 1, 2020·Journal of Alzheimer's Disease : JAD·Wenna DuanWeiying Dai

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