Simple, rapid, sensitive, and versatile SWNT-paper sensor for environmental toxin detection competitive with ELISA.

Nano Letters
Libing WangNicholas A Kotov

Abstract

Safety of water was for a long time and still is one of the most pressing needs for many countries and different communities. Despite the fact that there are potentially many methods to evaluate water safety, finding a simple, rapid, versatile, and inexpensive method for detection of toxins in everyday items is still a great challenge. In this study, we extend the concept of composites, impregnated porous fibrous materials, such as fabrics and papers, by single-walled carbon nanotubes (SWNTs), toward very simple but high-performance biosensors. They utilize the strong dependence of electrical conductivity through nanotubes percolation network on the width of nanotube-nanotube tunneling gap and can potentially satisfy all the requirements outlined above for the routine toxin monitoring. An antibody to the microcystin-LR (MC-LR), one of the common culprits in mass poisonings, was dispersed together with SWNTs. This dispersion was used to dip-coat the paper rendering it conductive. The change in conductivity of the paper was used to sense the MC-LR in the water rapidly and accurately. The method has the linear detection range up to 10 nmol/L and nonlinear detection up to 40 nmol/L. The limit of detection was found to be 0.6 nmol/L...Continue Reading

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Citations

Apr 23, 2013·Analytical and Bioanalytical Chemistry·Emilia W Nery, Lauro T Kubota
Jul 4, 2013·Analytical and Bioanalytical Chemistry·Natalia VilariñoLuis M Botana
Aug 21, 2013·Aquatic Toxicology·Shruti Pavagadhi, Rajasekhar Balasubramanian
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Jun 11, 2014·Advanced Materials·Xianfu WangGuozhen Shen
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