Simple Vaginal Trachelectomy: A Valuable Fertility-Preserving Option in Early-Stage Cervical Cancer

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
Marie PlanteJean Gregoire

Abstract

Radical trachelectomy is a valid alternative for the treatment of early-stage cervical cancer in young women who wish to preserve fertility potential. Recent data indicate that even less radical surgery could be performed in low-risk cases. The objective of our study was to evaluate the safety of simple vaginal trachelectomy and node assessment in patients with low-risk, early-stage cervical cancer (<2 cm). From May 2007 to July 2016, 35 women underwent a simple vaginal trachelectomy with laparoscopic sentinel lymph node mapping + pelvic node dissection. Data were collected prospectively in a computerized database. Descriptive statistics and Kaplan-Meier estimate were used for analysis. Patients' median age was 29 years, and 24 (69%) were nulliparous. Eight had stage IA1 with lymphovascular space invasion, 9 a stage IA2, and 18 a stage IB1. Nineteen (54%) had squamous histology, 13 (37%) had adenocarcinoma, and 3 had other histologic findings. The median operating room time was 148 minutes (90-240 minutes), and median blood loss was 50 mL (25-200 mL). On final pathology, lymph nodes were negative in all patients, except 2 cases with isolated tumor cells. Twenty-two patients (63%) had either no residual disease in the trachelect...Continue Reading

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Citations

Oct 12, 2018·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Neerja BhatlaRengaswamy Sankaranarayanan
Jan 19, 2019·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Neerja BhatlaJayashree Natarajan
Aug 10, 2020·Obstetrics and Gynecology·Evan S SmithJennifer J Mueller
May 18, 2018·Journal of Gynecologic Oncology·Kemal GungordukDavid Cibula
Jun 6, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Marie PlanteJean Gregoire
Dec 30, 2020·Journal of Minimally Invasive Gynecology·Jaden R KohnMindy S Christianson
Nov 24, 2020·Journal of Minimally Invasive Gynecology·Michelle L KuznickiPeter G Rose
Sep 7, 2021·Gynécologie, Obstétrique, Fertilité & Sénologie·M Bréban-KehlS Gouy

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