Simplified approach to low-frequency coherent anti-Stokes Raman spectroscopy using a sharp spectral edge filter

Optics Letters
Liqing RenDan Oron

Abstract

Coherent anti-Stokes Raman scattering (CARS) has found wide applications in biomedical research. Compared with alternatives, single-beam CARS is especially attractive at low frequencies. Yet, currently existing schemes necessitate a relatively complicated setup to perform high-resolution spectroscopy. Here we show that the spectral sharp edge formed by an ultra-steep long-pass filter is sufficient for performing CARS spectroscopy, simplifying the system significantly. We compare the sensitivity of the presented methodology with available counterparts both theoretically and experimentally. Importantly, we show that this method, to the best of our knowledge, is the simplest and most suitable for vibrational imaging and spectroscopy in the very low-frequency regime (<200  cm-1).

References

Aug 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·B Brooks, M Karplus
Jan 7, 2003·Physical Review Letters·Dan OronYaron Silberberg
Apr 14, 2007·Science·Dmitry PestovMarlan O Scully
Dec 18, 2010·Optics Express·Ori KatzYaron Silberberg
Dec 18, 2012·Journal of Biophotonics·Adrian F PegoraroAlbert Stolow
Oct 18, 2013·Nature·Takuro IdeguchiTheodor W Hänsch
Jan 27, 2015·Nature Photonics·Charles H CampMarcus T Cicerone
Jun 16, 2015·Optics Express·Sunil KumarYaron Silberberg
Oct 31, 2015·Annual Review of Biomedical Engineering·Chi ZhangJi-Xin Cheng

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