Simplified measurement of intra-access pressure.

Journal of the American Society of Nephrology : JASN
A BesarabT Lubkowski

Abstract

The measurement of intra-access pressure (P[IA]) normalized by mean arterial BP (MAP) helps detect venous outlet stenosis and correlates with access blood flow. However, general use of P(IA)/MAP is limited by time and special equipment costs. Bernoulli's equation relates differences between P(IA) (recorded by an external transducer as PT) and the venous drip chamber pressure, PDC; at zero flow, the difference in height (deltaH) between the measuring sites and fluid density determines the pressure deltaPH = P(IA) - P(DC) Therefore, P(DC) and PT measurements were correlated at six different dialysis units, each using one of three different dialysis delivery systems machines. Both dynamic (i.e., with blood flow) and static pressures were measured. Changes in mean BP, zero calibration errors, and hydrostatic height between the transducer and drip chamber accounted for 90% of the variance in P(DC), with deltaPH = -1.6 + 0.74 deltaH (r = 0.88, P < 0.001). The major determinants of static P(IA)/MAP were access type and venous outflow abnormalities. In grafts, flow averaged 555 +/- 45 ml/min for P(IA)/MAP > 0.5 and 1229 +/- 112 ml/min for P(IA)/MAP < 0.5. DeltaPH varied from 9.4 to 17.4 mmHg among the six centers and was related to del...Continue Reading

Citations

Jan 12, 2000·Current Opinion in Nephrology and Hypertension·J H Smits, P J Blankestijn
Mar 22, 2001·Kidney International·J H SmitsP J Blankestijn
Jul 28, 2001·Kidney International·G McDougal, R Agarwal
Sep 5, 2001·Kidney International·P McCarleyT A Ikizler
Apr 23, 2002·Kidney International·Laura M DemberJames S Kaufman
May 16, 2002·Seminars in Nephrology·William D PaulsonGazi B Zibari
May 7, 1999·Kidney International·S J SchwabD Beasley
Dec 3, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Pietro RavaniFabio Malberti
Feb 21, 2002·The International Journal of Artificial Organs·W KleinekofortV Wizemann
Sep 29, 2001·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·A BesarabS Frinak
Oct 2, 2004·Kidney International·Lawrence M SpergelEileen J Peacock
Apr 5, 2003·Kidney International·Gary R SirkenRasib Raja
Aug 4, 1999·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·R Agarwal, J L Davis
May 4, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·J J SandsT L Ortel
Sep 29, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M V DeVitaM F Michelis
Dec 5, 2008·Kidney International·Andrea CiandriniSilvio Cavalcanti
May 13, 2009·Hemodialysis International·Michael Allon, Michelle L Robbin
Aug 9, 2006·Seminars in Dialysis·Devasmita Choudhury
Dec 14, 2011·International Journal of Nephrology·Lalathaksha KumbarAnatole Besarab

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs
A BesarabS Frinak
The Journal of Vascular Access
W Kleinekofort
The International Journal of Artificial Organs
W KleinekofortV Wizemann
EDTNA/ERCA Journal : Official Journal of the European Dialysis and Transplant Nurses Association, European Renal Care Association
M PortováF Lopot
© 2022 Meta ULC. All rights reserved