PMID: 4403571Aug 26, 1972Paper

Simplified method for determining acetylator phenotype

British Medical Journal
H Schröder

Abstract

A chemical method has been developed for estimating the acetylator phenotype without the use of special equipment. One urine specimen taken after ingestion of sulphadimidine, sulphapyridine, or sulphasalazine is required. The acetylator phenotype was assessed correctly in 150 urine specimens from 100 healthy subjects. Between 15 and 25 specimens can be determined hourly. Urine specimens for the test can be stored for two weeks at 37 degrees C without any loss of drugs or their metabolites.

References

Mar 1, 1972·Journal of Medical Genetics·L C Eze, D A Evans
Jun 1, 1972·Journal of Medical Genetics·H Schröder, D A Evans
Dec 1, 1969·Journal of Medical Genetics·D A Evans
Aug 8, 1970·British Medical Journal·D W Russell

Citations

Jan 1, 1989·Rheumatology International·G J CarrollL M Tinsley
Jun 1, 1982·Diabetologia·G M ShenfieldR Tjokresetio
Jan 1, 1977·European Journal of Clinical Pharmacology·T Talseth, K H Landmark
Jan 1, 1983·European Journal of Clinical Pharmacology·W A Bogers, L Meems
Jan 1, 1989·Pharmacology & Therapeutics·D A Evans
Jan 1, 1980·Progress in Neuro-psychopharmacology·C Q MountjoyM Roth
May 28, 1983·Lancet·L Meems, W A Bogers
Dec 1, 1976·British Journal of Clinical Pharmacology·W CampbellT D Lawrie
Sep 1, 1978·British Journal of Clinical Pharmacology·E F MarshallM Roth
Dec 1, 1975·Australian and New Zealand Journal of Medicine·S N Hunyor
Apr 1, 1979·Annals of the Rheumatic Diseases·D H LawsonA Solomon
Dec 1, 1985·Annals of the Rheumatic Diseases·T PullarH A Capell
May 1, 1986·Annals of the Rheumatic Diseases·R S AmosM S Greaves
Aug 2, 1980·British Medical Journal·R F BingJ D Swales
Aug 1, 1984·Journal of Medical Genetics·D A Evans
Sep 1, 1973·Postgraduate Medical Journal·P CochraneS Ehsanullah
Jul 1, 1979·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·P R ReevesH T Jepson
Jan 1, 1980·British Journal of Clinical Pharmacology·S E SmithP J Tyrer
Oct 1, 1986·British Journal of Clinical Pharmacology·D SuhardjonoG M Shenfield
Nov 1, 1982·British Journal of Clinical Pharmacology·B K Park
Apr 1, 1984·British Journal of Clinical Pharmacology·D M GrantW Kalow
Jun 1, 1987·Alimentary Pharmacology & Therapeutics·D A BurkeA T Axon
Sep 1, 1982·British Journal of Clinical Pharmacology·I D WatsonJ A Thomson
Jan 4, 1975·The Medical Journal of Australia·J W Freeman, L W Knight
Jun 1, 1990·Seminars in Arthritis and Rheumatism·M J WijnandsL B van de Putte

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Nodding Syndrome

Nodding Syndrome is a neurological and epileptiform disorder characterized by psychomotor, mental, and growth retardation. Discover the latest research on Nodding Syndrome here.

LRRK2 & Microtubules

Mutations in the LRRK2 gene are risk-factors for developing Parkinson’s disease (PD). LRRK2 mutations in PD have been shown to enhance its association with microtubules. Here is the latest research.