PMID: 4403571Aug 26, 1972Paper

Simplified method for determining acetylator phenotype

British Medical Journal
H Schröder


A chemical method has been developed for estimating the acetylator phenotype without the use of special equipment. One urine specimen taken after ingestion of sulphadimidine, sulphapyridine, or sulphasalazine is required. The acetylator phenotype was assessed correctly in 150 urine specimens from 100 healthy subjects. Between 15 and 25 specimens can be determined hourly. Urine specimens for the test can be stored for two weeks at 37 degrees C without any loss of drugs or their metabolites.


Mar 1, 1972·Journal of Medical Genetics·L C Eze, D A Evans
Jun 1, 1972·Journal of Medical Genetics·H Schröder, D A Evans
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